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Evidence-based GLP-1 & peptide discussion since 2023
ForumsMASH / Liver DiseaseHas anyone dealt with mash resolution without worsening fibrosis? Page 7

Has anyone dealt with mash resolution without worsening fibrosis?

KevinCompounds Thu, Oct 31, 2024 at 11:40 AM 45 replies 2,606 viewsPage 7 of 9
sarah_TO
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Toronto, CA
Nov 5, 2024 at 9:08 PM#31

Adding the clinical framing, because it changes how the question reads. Whatever the answer turns out to be, the method for getting there is the same: state the assumption, do the arithmetic in public, and invite the correction. That is slower than asserting, and it is the only version that survives being wrong.

49 22andrew_nyc, Dr.EndoEP, GraceAZ_72 and 46 others
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LeilaHI
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Jan 2025
Honolulu, HI
Nov 6, 2024 at 4:11 AM#32
sarah_TO said:
Whatever the answer turns out to be, the method for getting there is the same: state the assumption, do the arithmetic in public, and invite the…

Can confirm. Same sequence, different timescale.

50 23VendorMark, COA_Karl, MikeFit_NJ and 47 others
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wei_SG
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Nov 2024
Singapore, SG
Nov 6, 2024 at 11:14 AM#33
sarah_TO said:
Whatever the answer turns out to be, the method for getting there is the same: state the assumption, do the arithmetic in public, and invite the…

Adding the part of the answer the thread has not reached. The honest answer is that the effect is real, the magnitude is contested, and the individual variation is larger than either. Those three things can all be true at once, and most arguments here are two people holding different parts of that.

Last edited: Nov 6, 2024 at 12:14 PM
1 24Dr.MetabolicMD
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SleepDoc_PDX
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Portland, OR
Nov 6, 2024 at 6:17 PM#34

The figures, for anyone assembling their own picture. For anyone reading later: the numbers in this thread are worth checking against a primary source before you act on them, including mine. Half the figures circulating in this community trace back to a secondary summary that dropped a qualifier.

Happy to go further on any of that.

Last edited: Nov 6, 2024 at 9:17 PM
2 0sophie_paris, mel_PDX
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SkepticalSean
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Jan 2025
Maine
Nov 7, 2024 at 1:20 AM#35

One thing that is still open after sarah_TO’s answer:

What would you measure differently if you were starting again?

3 1Dr.LipidDallas, alex_tucson, kevin_tulsa
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