paige_pharma said:

It helps to ask what evidence would change your mind before you look at any.

This matches mine closely enough to be worth saying so out loud.

The figures, for anyone assembling their own picture. Practical: whatever you change, write down the date and the reason. In three months the reason is what you will have forgotten, and the reason is what makes the record worth having.

Following on from dave_SLC — and this may be the naive question:

How would you tell the difference between that and the alternative explanation?

FDA_TrackerJim said:

Practical: whatever you change, write down the date and the reason.

This is where I part company with the consensus forming above. The counter-case has not been addressed. Somebody upthread described the situation that does not fit, and the thread moved on rather than engaging with it, which is the failure mode this board is supposed to avoid.

Moderator note: reminder that nothing in this thread is medical advice, and that clinical claims need a source.