roxy_nash said:

Electrolyte monitoring on hydration — especially important during early titration when GI effects are most pronounced: Sodium: 140 mEq/L (normal, but…

Agreed, with the usual condition: that holds for the average and this board is a collection of individuals. A population claim and a personal prediction are different things and get quoted interchangeably.

hannah_MT said:

Agreed, and the practical implication is not to over-read a single eGFR during a period of rapid loss and altered hydration.

Saving this. It is the first explanation that did not require me to already understand it. Sending this to two other people who asked me the same thing last week.

roxy_nash said:

Electrolyte monitoring on hydration — especially important during early titration when GI effects are most pronounced: Sodium: 140 mEq/L (normal, but…

Filing a mild objection. Mild because I might be wrong; an objection because nobody has addressed the case that does not fit. Pushing back on the anecdote-stacking. Twenty people reporting the same thing is twenty samples from the same self-selected pool, not twenty independent confirmations.

I would rather be corrected than agreed with, if it comes to it.

One concrete data point for the thread. For anyone reading later: the numbers in this thread are worth checking against a primary source before you act on them, including mine. Half the figures circulating in this community trace back to a secondary summary that dropped a qualifier.

Moderator note: leaving this open. It is being argued well and the disagreement is the useful part. Report rather than reply if it drifts again.