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Evidence-based GLP-1 & peptide discussion since 2023
ForumsSide Effects & ManagementI literally cannot eat more than 3 bites help — anyone have experience? Page 2

I literally cannot eat more than 3 bites help — anyone have experience?

Dr.DermMIA Fri, Oct 18, 2024 at 6:24 PM 37 replies 2,114 viewsPage 2 of 8
TirzTom
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Oct 19, 2024 at 4:19 AM#6

One concrete data point for the thread. Give anything pharmacological four weeks before you judge it, and give anything measured weekly a four-point rolling average before you call it a trend.

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gary_naperville
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Oct 19, 2024 at 8:14 AM#7

A narrower follow-up, since the general answer is now clear:

Whether holding at a lower dose for longer actually reduces total side-effect burden or just spreads it out?

Last edited: Oct 19, 2024 at 11:14 AM
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sophie_paris
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Oct 19, 2024 at 12:09 PM#8
TirzTom said:
Give anything pharmacological four weeks before you judge it, and give anything measured weekly a four-point rolling average before you call it a…

There is a second half to this that has not been said yet. The mechanism and the magnitude are separate questions. Agreeing that something happens says nothing about whether it happens enough to act on.

Last edited: Oct 19, 2024 at 5:09 PM
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Dr.DermMIA
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Oct 19, 2024 at 4:04 PM#9

Closing the loop on my own question.

Update. It was not the dose, it was that I had stopped drinking anything because drinking made me feel full. Fixing that fixed most of it.

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josh_phd_bmore
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Oct 20, 2024 at 10:51 AM#10
sophie_paris said:
The mechanism and the magnitude are separate questions.

Agreed on adaptation, with a caveat: adaptation applies to gastric emptying and not to everything. If your problem is the aversion rather than the fullness, waiting does less, because the aversion is central and it is the mechanism working as intended.

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