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Evidence-based GLP-1 & peptide discussion since 2023
ForumsCOA & Analytical TestingMy vendor COA looks sketchy - can someone take a look — anyone have experience? Page 2

My vendor COA looks sketchy - can someone take a look — anyone have experience?

lucas_SP_BR Mon, Aug 25, 2025 at 4:41 AM 7 replies 1,280 viewsPage 2 of 2
DataDave
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Aug 25, 2025 at 7:19 AM#6
Dr.ReproEndo said:
Prices dramatically below market are the strongest single signal, and the reason is arithmetic rather than suspicion.

I disagree that testing history is decisive. It tells you what a supplier did when they were being watched. Continuity of behaviour under stress — a late shipment, a failed test, a complaint — is more predictive than any run of good results.

1 21VendorMark
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LabKate
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Aug 25, 2025 at 8:20 AM#7

The figures, for anyone assembling their own picture. The four things to check on any report, in order: does it name your batch, who commissioned it, what method was used, and does it report content as well as purity. A report failing any of those is weak evidence regardless of the percentage on it.

Last edited: Aug 25, 2025 at 11:20 AM
50 20laura_annarbor, JenMemphis, pat_auckland and 47 others
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Dr.EM_Chicago
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Aug 25, 2025 at 9:21 AM#8
DataDave said:
I disagree that testing history is decisive.

Adding the part of the answer the thread has not reached. Inter-laboratory variation comes from real methodological differences, not sloppiness: which reference standard was used and how it was itself calibrated, the gradient and column, the detection wavelength, and where the integration baseline was drawn. A percentage point or two between competent labs is expected. What is not expected is a large gap, and the usual explanation there is that one report is not of the batch in your hand.

49 19Dr.ReproEndo, lucas_SP_BR, lisa_labSD and 46 others
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RickReta_CO
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Aug 25, 2025 at 10:22 AM#9

Following on from TomFromTexas — and this may be the naive question:

What a vetting checklist should actually contain, as opposed to a list of things that are easy to fake?

Last edited: Aug 25, 2025 at 3:22 PM
48 18tommy_boulder, hyun_seoul, jim_asheville and 45 others
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lucas_SP_BR
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Aug 25, 2025 at 3:16 PM#10

Reporting back.

Went back through my own correspondence with an earlier supplier and the warning signs were all there in the replies, weeks before the quality changed. I was reading the product and not the behaviour.

42 15tampaLisa73, KarenAZ_mom, zoe_NC and 39 others
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