Dr.DermMIA said:

If two explanations both fit, the useful question is which one predicts something the other does not.

Same experience, arrived at from the opposite direction. I had assumed I was the exception until I read this.

Dr.DermMIA said:

If two explanations both fit, the useful question is which one predicts something the other does not.

Coming at Dr.DermMIA’s question from a different direction. The mechanism and the magnitude are separate questions. Agreeing that something happens says nothing about whether it happens enough to act on.

Moderator note: good thread. Keeping it here rather than moving it, because the question is general enough to be useful.

One thing that is still open after Dr.DermMIA’s answer:

What would you measure differently if you were starting again?

Dr.RaviCardio said:

The mechanism and the magnitude are separate questions.

Filing a mild objection. Mild because I might be wrong; an objection because nobody has addressed the case that does not fit. This treats a plausible mechanism as a demonstrated one. Plausible is where you start looking, not where you stop.