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Evidence-based GLP-1 & peptide discussion since 2023
ForumsCOA & Analytical TestingMass spectrometry for peptide identity verification — March 2026 Page 5

Mass spectrometry for peptide identity verification — March 2026

hannah_MT Sat, Jul 12, 2025 at 7:00 AM 26 replies 1,892 viewsPage 5 of 6
Dr.PathRoch
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Jul 18, 2025 at 9:10 PM#21

One concrete data point for the thread. Practical: whatever you change, write down the date and the reason. In three months the reason is what you will have forgotten, and the reason is what makes the record worth having.

25 23MikeFit_NJ, InsuranceTom, WendyG_ATL and 22 others
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pete_RVA
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Richmond, VA
Jul 19, 2025 at 9:32 AM#22

One thing that is still open after NurseKim_ATL’s answer:

Was that from a primary source or from a summary of one?

Last edited: Jul 19, 2025 at 2:32 PM
26 24Dr.Martinez, mike_mod, SarahChen_PharmD and 23 others
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Dr.EndoEP
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Oct 2024
El Paso, TX
Jul 19, 2025 at 9:54 PM#23
Dr.PathRoch said:
Practical: whatever you change, write down the date and the reason.

Pushing back on Dr.PathRoch here. The counter-case has not been addressed. Somebody upthread described the situation that does not fit, and the thread moved on rather than engaging with it, which is the failure mode this board is supposed to avoid.

27 0FranDenver, Dr.BariatricHTX, LindaRN_retired and 24 others
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SkepticalSean
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Maine
Jul 20, 2025 at 10:15 AM#24
Dr.PathRoch said:
Practical: whatever you change, write down the date and the reason.

True, with the qualification that this is a self-selected group. The people for whom it did not work post less, and that shapes everything we think we know.

Last edited: Jul 20, 2025 at 2:15 PM
28 1tammy_FL, Dr.LipidDallas, alex_tucson and 25 others
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HPLC_Greg
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Research Triangle, NC
Jul 20, 2025 at 10:36 PM#25
Dr.PathRoch said:
Practical: whatever you change, write down the date and the reason.

Thank you for spelling out the reasoning rather than just the conclusion.

Last edited: Jul 21, 2025 at 4:36 AM
29 2SaraMom3, Dr.MetabolicMD, RetaRick_CA and 26 others
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