🍪 CompoundTalk uses cookies to improve your experience, analyze traffic, and personalize content. By continuing to use this site, you agree to our Cookie Policy.
Evidence-based GLP-1 & peptide discussion since 2023
ForumsSide Effects & ManagementFatigue on semaglutide — 6 month update Page 2

Fatigue on semaglutide — 6 month update

SurmountFan_IN Thu, May 16, 2024 at 9:08 AM 14 replies 2,071 viewsPage 2 of 3
Dr.RenalNash
VIP Member
1,234
7,890
Mar 2024
Nashville, TN
May 17, 2024 at 1:48 PM#6

For anyone in a physically demanding role:

  • Start your medication on a stretch of days off if possible, so you can gauge your response
  • Don't under-eat. Set a caloric floor (1500+ for active jobs) and hit it even when not hungry
  • Frontload your calories — bigger breakfast before a shift, not a big dinner after
  • Electrolyte packets (LMNT, Liquid IV, etc.) during shifts
  • If fatigue is severe enough to impact patient safety or job performance, that's a conversation with your prescriber about dosing schedule or slower titration

The fatigue is almost always worst in the first 4-6 weeks and improves as your body adapts to both the drug and the new caloric baseline.

Last edited: May 17, 2024 at 6:48 PM
44 14wei_SG, cory_ATX, lori_vegas and 41 others
Reply Quote Save Share Report
LarryQC_SD
Senior Member
2,123
9,876
Jan 2024
San Diego, CA
May 18, 2024 at 1:14 AM#7

One thing that's helped me enormously: strategic caffeine timing. I have coffee at 7am and green tea at 1pm. Not more, not later. Gives me two energy bumps without wrecking my sleep. And I eat a high-protein snack (Greek yogurt, handful of almonds, string cheese) between meals to prevent energy crashes. Small things but they add up.

43 13paul_denver, TinaHashiRN, robert_kc and 40 others
Reply Quote Save Share Report
SallyK_inj
Member
567
2,345
Jul 2024
Iowa
May 18, 2024 at 12:41 PM#8

Okay, reality check received. I tracked everything carefully yesterday and I ate... 1,050 calories. I'm basically intermittent starving, not intermittent fasting. Going to make a conscious effort to hit 1,400 minimum starting today and get bloodwork done this week. Thank you all.

42 12oliver_london, tane_welly, Dr.PathRoch and 39 others
Reply Quote Save Share Report

PeptideMeter — Independent Peptide Analytics

Community-driven peptide testing and vendor rating platform. Transparent results. Unbiased analysis. Trusted by thousands.

View Results

Similar Threads

Nausea incidence by dose tier — STEP and SURMOUNT meta-analysis16 replies
Constipation on GLP-1: pathophysiology and fiber protocol5 replies
Alopecia on GLP-1 — telogen effluvium differential diagnosis3 replies
Gallbladder disease risk — cholelithiasis data from clinical trials12 replies
Pancreatitis risk assessment — pooled safety analysis15 replies
ForumsNewTrendingMembersAccount

Log In

Forgot password?
No account? Register