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Evidence-based GLP-1 & peptide discussion since 2023
ForumsProgress & Lab ResultsMarathon PR after 80 lbs weight loss — anyone have experience?

Marathon PR after 80 lbs weight loss — anyone have experience?

Dr.LipidDallas Mon, Jul 22, 2024 at 10:32 PM 59 replies 2,635 viewsPage 1 of 12
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Dr.LipidDallas
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Dallas, TX
Jul 22, 2024 at 10:32 PM#1

Nine weeks flat after five months of steady loss, same dose, same routine, and I cannot tell whether to wait or change something.

What I am after is how to distinguish a genuine plateau from measurement noise and creeping intake, before changing anything.

I have searched first, so if this is covered somewhere point me at it and I will read it.

37 7pam_stl, wei_SG, cory_ATX and 34 others
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LarryQC_SD
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Jan 2024
San Diego, CA
Jul 22, 2024 at 11:02 PM#2
Dr.LipidDallas said:
Nine weeks flat after five months of steady loss, same dose, same routine, and I cannot tell whether to wait or change something.

Plateau breaking story with a stall: I stalled at 216 lbs for 5 weeks. Tried everything — calorie cycling, increased exercise, more water. Nothing worked.

What finally broke the plateau: switching from evening to morning injection. Lost 7 lbs in the next 2 weeks. Plateaus are temporary — they always break if you stay consistent.

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Dr.AddMedPHL
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Mar 2024
Philadelphia, PA
Jul 22, 2024 at 11:32 PM#3
LarryQC_SD said:
Plateau breaking story with a stall: I stalled at 216 lbs for 5 weeks.

Agreeing with LarryQC_SD, and the qualification matters more than the agreement. Most reported plateaus are not plateaus. Weight is a noisy signal — daily variation of one to two kilograms from glycogen, sodium and gut contents — so a fortnight of flat readings is well inside the noise band. Before concluding anything, look at a rolling weekly average over at least four weeks and at a tape measure, because recomposition shows up in circumference before it shows up in weight. Then track intake honestly for a week: appetite suppression fades unevenly, and intake creeping back up is the single commonest cause.

Last edited: Jul 23, 2024 at 1:32 AM
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SandraNC_45
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Sep 2024
Charlotte, NC
Jul 23, 2024 at 12:02 AM#4
Dr.LipidDallas said:
Nine weeks flat after five months of steady loss, same dose, same routine, and I cannot tell whether to wait or change something.

Same pattern here, and in the same order. I had assumed I was the exception until I read this.

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julia.endo
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Cincinnati, OH
Jul 23, 2024 at 2:50 AM#5

Clinical perspective, offered as context rather than as advice. It helps to ask what evidence would change your mind before you look at any. If nothing would, the discussion is not about evidence, and it is better to say so early than to spend nine posts discovering it.

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