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Evidence-based GLP-1 & peptide discussion since 2023
ForumsCOA & Analytical TestingHas anyone dealt with moisture content analysis for lyophilized peptides? Page 8

Has anyone dealt with moisture content analysis for lyophilized peptides?

NauseaFreeNow Sun, Mar 16, 2025 at 5:34 AM 42 replies 1,836 viewsPage 8 of 9
CanadaChris
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May 26, 2025 at 3:39 AM#36
Dr.PeteFamMed said:
Keep the original post as written when you update it, and add the correction underneath.

I read this differently from Dr.PeteFamMed, on substance rather than tone. I would resist the confidence. Half of what this board was certain about two years ago has since been quietly dropped, and nobody went back to correct the threads.

44 17Dr.EM_Chicago, pete_RVA, CarlaRPh_TPA and 41 others
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mike_mod
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May 30, 2025 at 3:53 AM#37
Dr.PeteFamMed said:
Keep the original post as written when you update it, and add the correction underneath.

Correct as far as it goes. The part it does not cover is what to do when the honest answer is "not enough data", which is more often than anyone likes.

Last edited: May 30, 2025 at 5:53 AM
45 18TomTeleRx, DoseLogDan, SleepFixSam and 42 others
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sean_dublin
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Jun 3, 2025 at 4:10 AM#38
Dr.PeteFamMed said:
Keep the original post as written when you update it, and add the correction underneath.

This answered a question I did not know how to ask. I will report back once I have actually tried it.

Last edited: Jun 3, 2025 at 5:10 AM
46 19gary_naperville, sean_dublin, hannah_MT and 43 others
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NurseLeah_Nash
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Jun 7, 2025 at 4:29 AM#39

Clinical perspective, offered as context rather than as advice. Whatever the answer turns out to be, the method for getting there is the same: state the assumption, do the arithmetic in public, and invite the correction. That is slower than asserting, and it is the only version that survives being wrong.

47 20Dr.KarenChen, Dr.NateNeph, PharmD_Rodriguez and 44 others
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nancy_portland
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Jun 11, 2025 at 4:50 AM#40
NurseLeah_Nash said:
Whatever the answer turns out to be, the method for getting there is the same: state the assumption, do the arithmetic in public, and invite the…

This is my experience too, for whatever a second data point is worth. Nothing to add that would improve it.

Last edited: Jun 11, 2025 at 5:50 AM
19 17claudia_zurich, nancy_portland, rick_sfbay and 16 others
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