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Evidence-based GLP-1 & peptide discussion since 2023
ForumsCOA & Analytical TestingCOA red flag compilation — what worked for you? Page 6

COA red flag compilation — what worked for you?

PharmD_Rodriguez Mon, Jan 20, 2025 at 6:03 PM 28 replies 1,920 viewsPage 6 of 6
LabKate
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Oregon
Apr 6, 2025 at 5:43 PM#26

Following on from NurseKim_ATL — and this may be the naive question:

What did you change at the same time, and can you separate the two now?

2 0JenMemphis, pat_auckland
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NeuroNate
Senior Member
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Chicago, IL
Apr 16, 2025 at 8:48 AM#27
dave_SLC said:
Say what you would expect to see if you were wrong, before you look.

Careful with the causal language. Two things moving together in a period when five things changed is not a mechanism, and stating it as one makes the thread less useful to somebody reading it later.

3 1wendy_avl, jason_paloalto, Dr.LeslieOBGYN
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paul_denver
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Apr 25, 2025 at 11:47 PM#28
dave_SLC said:
Say what you would expect to see if you were wrong, before you look.

Correct as far as it goes. The part it does not cover is what to do when the honest answer is "not enough data", which is more often than anyone likes.

4 2wendy_avl, jason_paloalto, Dr.LeslieOBGYN and 1 other
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mia_MS2
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Ann Arbor, MI
May 5, 2025 at 2:40 PM#29
dave_SLC said:
Say what you would expect to see if you were wrong, before you look.

This is exactly what I could not find anywhere else. Sending this to two other people who asked me the same thing last week.

5 3steve_okc, dave_SLC, FDA_TrackerJim and 2 others
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PharmD_Rodriguez
Senior Member
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Miami, FL
May 15, 2025 at 5:28 AM#30

Reporting back.

Purity and content being different measurements was the piece I was missing. The vial was overfilled and pure, which is a very different problem from the one I thought I had.

27 0MeganSA_TX, LarryQC_SD, wanda_boise and 24 others
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