Dr.PeteFamMed said:The mental-health dimension is under-measured in the trial literature and the reports here are consistent enough to take seriously.
Agreed, and for anyone with an eating-disorder history this needs a clinician in the loop rather than a forum. The same drug can be therapeutic in binge-eating disorder and actively harmful in a restrictive disorder.
NauseaFreeNow said:Agreed on the target, with the caveat that reference weight and current weight are different numbers.
Saving this. It is the first explanation that did not require me to already understand it.
Dr.PeteFamMed said:The mental-health dimension is under-measured in the trial literature and the reports here are consistent enough to take seriously.
Filing a mild objection. Mild because I might be wrong; an objection because nobody has addressed the case that does not fit. I would be careful about how confidently the flatness reports get attributed. Rapid weight loss, a large deficit and disrupted sleep produce low mood on their own, and separating that from a drug effect is genuinely hard.
Happy to go further on any of that.
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Shop Reference StandardsAdding the numbers, since they settle part of this. One practical note: write down what you did and when, before you need it. Reconstructing a timeline from memory three months later is how people end up unable to answer the one question that would have resolved it.
Moderator note: two posts asking for a source have been merged into one. Please search the thread before asking again. Carry on.