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ForumsNutrition & SupplementationKeto vs Mediterranean vs high-protein — which diet pairs best with GLP-1?

Keto vs Mediterranean vs high-protein — which diet pairs best with GLP-1?

DebRD_ATL Sat, May 9, 2026 at 2:47 PM 21 replies 912 viewsPage 1 of 5
DebRD_ATL
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May 9, 2026 at 2:47 PM#1

I tracked honestly for two weeks and averaged 68g of protein against a target of about 120g. That gap is the whole problem and no meal plan I have found is written for it.

What I am after is whether the RDA is the wrong reference entirely during rapid weight loss, and what the actual target should be.

Tell me what I have not thought of.

49 19BiostatsBrad, PeptideSynthNJ, Dr.KarenChen and 46 others
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BariatricNurseD
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May 9, 2026 at 3:47 PM#2

Short answer first, then the reasoning. The RDA is the wrong reference and it is worth understanding why. 0.8 g/kg is the intake at which nitrogen balance is not negative in healthy weight-stable adults — a floor for deficiency prevention, not an optimum, and derived in a population that is not in a deficit. In a substantial energy deficit, protein requirement rises because amino acids are being oxidised for energy and because muscle protein synthesis is blunted. The literature on preserving lean mass during weight loss lands around 1.4 to 2.0 g/kg of reference body weight, which is roughly two to two and a half times the RDA.

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Dr.SportsMedIN
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May 9, 2026 at 4:47 PM#3
BariatricNurseD said:
The RDA is the wrong reference and it is worth understanding why.

Agreed on the target, with the caveat that reference weight and current weight are different numbers. Using current weight at the start of a large loss produces a target that is both unachievable and unnecessary.

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andrew_nyc
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May 9, 2026 at 5:48 PM#4
DebRD_ATL said:
I tracked honestly for two weeks and averaged 68g of protein against a target of about 120g.

Same position here, arrived at the long way round. Distribution matters less than total but it is not nothing. Roughly 25 to 40g per sitting with enough leucine to trigger synthesis, three or four times a day, is more effective than the same total in one enormous evening meal — and on a suppressed appetite the enormous evening meal is the one you will not finish anyway.

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TrialTracker_MD
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May 9, 2026 at 11:38 PM#5

From the other side of the consultation, briefly.

DEXA scan update relevant to protein intake:

Scanned at months 0, 6, and 12. Here are the body comp numbers:

BaselineMonth 6Month 12
Total mass264 lbs234 lbs201 lbs
Fat mass104 lbs84 lbs51 lbs
Lean mass157 lbs147 lbs158 lbs
Body fat %41%33%25%

Lean mass preserved — actually GAINED 1-2 lbs thanks to progressive overload + 1.4g/kg protein. The protein intake discussion needs to include body comp data, not just scale weight.

45 15lori_vegas, Dr.PulmRoch, maya_sedona and 42 others
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