carl_compliance said:

The useful move here is to separate what is established from what is widely repeated.

No disagreement, though the timescale matters more than the mechanism here. Most of what looks like a difference in kind turns out to be a difference in how long somebody waited.

LibrarianMeg said:

Right, and one flattering data point from a group buy is not consistency.

Thank you — that is the clearest version of this I have read, and I have read a lot of them. Taking it to my next appointment.

carl_compliance said:

The useful move here is to separate what is established from what is widely repeated.

I am going to disagree with the direction of travel here. The thread has converged on the tidiest answer rather than the best-supported one, and those are not the same thing.

The figures, for anyone assembling their own picture. If you are going to change something, change one thing and give it long enough to express itself. Four weeks is the usual minimum for anything pharmacological on this board, and two weeks of data has told you almost nothing.

Moderator note: good thread. Keeping it here rather than moving it, because the question is general enough to be useful.