PharmacoVig_BOS said:

If you are comparing against somebody else’s result, check that you are comparing the same measurement taken the same way.

Pushing back on PharmacoVig_BOS here. Filing an objection on the n=1 problem. Personal experience is genuine evidence about one person and very weak evidence about anybody else, and this thread keeps promoting the first into the second.

PharmacoVig_BOS said:

If you are comparing against somebody else’s result, check that you are comparing the same measurement taken the same way.

True, and it depends on a baseline nobody has stated. Without knowing where someone started, the same number can be an excellent result or a disappointing one.

PharmacoVig_BOS said:

If you are comparing against somebody else’s result, check that you are comparing the same measurement taken the same way.

This answered a question I did not know how to ask. Printing the relevant bit and taking it with me.

Adding the clinical framing, because it changes how the question reads. The honest answer is that the effect is real, the magnitude is contested, and the individual variation is larger than either. Those three things can all be true at once, and most arguments here are two people holding different parts of that.

NurseKim_ATL said:

The honest answer is that the effect is real, the magnitude is contested, and the individual variation is larger than either.

Second this. Posting only so the count is not one.