Following on from Dr.PathRoch — and this may be the naive question:

How long did you give it before you decided it was working?

hank_denver said:

Quick syringe math for dosing arithmetic dosing: if your vial is reconstituted at 5mg/2mL, that's 2.5mg/mL.

Sharing my dosing arithmetic titration experience with compounded semaglutide — I have been tracking injection volumes meticulously:

Using 5mg/2mL concentration with 1cc insulin syringes:

• Month 1: 10 units (0.25mg) — mild appetite reduction
• Month 2: 20 units (0.5mg) — significant appetite suppression
• Month 3: 30 units (0.75mg) — custom intermediate dose
• Month 4: 40 units (1.0mg) — optimal for me, staying here

The beauty of compounded vials is you can do custom intermediate doses. My provider was great about tailoring to my response.

hank_denver said:

Quick syringe math for dosing arithmetic dosing: if your vial is reconstituted at 5mg/2mL, that's 2.5mg/mL.

Comparison of compounded dosing arithmetic delivery formats I've tried:

I use lyophilized vials for cost and stability. The reconstitution takes 30 seconds once you've done it a few times.

hank_denver said:

Quick syringe math for dosing arithmetic dosing: if your vial is reconstituted at 5mg/2mL, that's 2.5mg/mL.

That reframing is the part I needed. I will report back once I have actually tried it.

patPC_UT said:

Comparison of compounded dosing arithmetic delivery formats I've tried: Format Pros Cons Lyophilized vial Longest shelf life, lowest cost Requires…

For anyone reconstituting dosing arithmetic peptides: the water-to-powder ratio determines your concentration. Here's my reference:

More water = easier to measure small doses but vial runs out faster. Find the balance that works for your dose.