PharmD_Rodriguez said:

The pattern that distinguishes a bad batch from an exit is behaviour rather than product.

I disagree that testing history is decisive. It tells you what a supplier did when they were being watched. Continuity of behaviour under stress — a late shipment, a failed test, a complaint — is more predictive than any run of good results.

PharmacoVig_BOS said:

Six orders from the same supplier over eight months, every one independently tested, and the consistency is the part worth reporting rather than any…

Vendor reputation tracking for vendor vetting: I maintain a personal spreadsheet with every order I've placed — date, vendor, batch number, Janoshik result, personal efficacy assessment (1-5 scale), and any issues.

After 23 orders across 5 vendors: average purity 98.7%, zero sterility concerns, 0 shipping issues (all resolved). This data gives me confidence in my current source and documentation if issues arise.

I encourage everyone to track their orders systematically. Community data aggregation makes us all safer.

LabKate said:

I disagree that testing history is decisive.

There is a second half to this that has not been said yet. The mechanism and the magnitude are separate questions. Agreeing that something happens says nothing about whether it happens enough to act on.

A narrower follow-up, since the general answer is now clear:

How people are distinguishing a supplier having a bad batch from a supplier on the way out?

OP back with an update, since a thread like this is useless without one.

Went back through my own correspondence with an earlier supplier and the warning signs were all there in the replies, weeks before the quality changed. I was reading the product and not the behaviour.