sarah_TO said:

PCOS success story with glycaemic control: as someone with polycystic ovary syndrome, this medication has been transformative beyond weight loss.

True, with the qualification that this is a self-selected group. The people for whom it did not work post less, and that shapes everything we think we know.

RickReta_CO said:

My labs after 9 months on glycaemic control: A1C 6.3%, fasting glucose 93 mg/dL, fasting insulin 8 uIU/mL.

Saving this. It is the first explanation that did not require me to already understand it. Sending this to two other people who asked me the same thing last week.

sarah_TO said:

PCOS success story with glycaemic control: as someone with polycystic ovary syndrome, this medication has been transformative beyond weight loss.

I read this differently from sarah_TO, on substance rather than tone. I think the framing smuggles in the conclusion. Ask it the other way round and the obvious answer reverses, which usually means the question is doing the work.

The figures, for anyone assembling their own picture. Keep the original post as written when you update it, and add the correction underneath. An edited-away mistake is invisible to the next person who makes it.

Moderator note: good thread. Keeping it here rather than moving it, because the question is general enough to be useful.