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ForumsDosing & ProtocolsSemaglutide PK modeling — anyone have experience? Page 6

Semaglutide PK modeling — anyone have experience?

anna.melb_AU Fri, Jan 31, 2025 at 11:07 AM 31 replies 2,196 viewsPage 6 of 7
Dr.EM_Chicago
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Mar 15, 2025 at 1:05 PM#26
roxy_nash said:
The version of this that has an answer is narrower than the version being asked.

Coming at roxy_nash’s question from a different direction. Start from the measurement rather than the conclusion. Almost every disagreement here turns out to be two people measuring different things and comparing the numbers anyway.

10 8jim_asheville, matt_MKE, Dr.ReproEndo and 7 others
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BethLabQueen
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Mar 20, 2025 at 9:34 PM#27

The figures, for anyone assembling their own picture. The boring version of this is the one that works, and the boring version is: measure a baseline, change one variable, wait, measure again under the same conditions. Nobody wants that answer and it is still the answer.

11 9Dr.PulmRoch, maya_sedona, stefan_berlin and 8 others
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CanadaChris
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Mar 26, 2025 at 6:00 AM#28

A narrower follow-up, since the general answer is now clear:

Whether anyone has held at a sub-maximal dose long term and kept the result, or whether the maintenance data only exists at 2.4mg?

12 10maya_sedona, stefan_berlin, Dr.EM_Chicago and 9 others
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RetaRick_CA
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Mar 31, 2025 at 2:23 PM#29
BethLabQueen said:
The boring version of this is the one that works, and the boring version is: measure a baseline, change one variable, wait, measure again under the…

Careful with the causal language. Two things moving together in a period when five things changed is not a mechanism, and stating it as one makes the thread less useful to somebody reading it later.

13 11nick_newbie, DadBodDave, AmyNC_wife and 10 others
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anna.melb_AU
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Apr 5, 2025 at 10:43 PM#30

Closing the loop on my own question.

Update since I posted: I held at 1.7mg for a further twelve weeks and lost another 4kg slowly, which settles it for me. I was escalating because the number was available, not because I had stopped responding.

35 8Dr.LipidDallas, alex_tucson, kevin_tulsa and 32 others
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