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ForumsMetabolic Health & DiabetesGLP-1 and gluconeogenesis — my results so far Page 3

GLP-1 and gluconeogenesis — my results so far

carlos_SATX Tue, Mar 10, 2026 at 7:15 AM 11 replies 875 viewsPage 3 of 3
Dr.BariatricHTX
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Mar 11, 2026 at 8:46 AM#11
chris_chi24 said:
Insulin sensitivity test (HOMA-IR) on glycaemic control — arguably the most important metabolic marker most people aren't tracking: HOMA-IR = (fasting…

Agreed on the substance. I would put less weight on the timescale, because two months of anything is not enough to distinguish a trend from a wobble.

29 2CarlaRPh_TPA, steph_laguna, fiona_glasgow and 26 others
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Dr.RheumBOS
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Mar 11, 2026 at 4:50 PM#12
KetoKyle said:
Fasting insulin is the lab my functional medicine doctor cares about most for glycaemic control: it's a much earlier marker of metabolic dysfunction…

Saving this. It is the first explanation that did not require me to already understand it.

Last edited: Mar 11, 2026 at 10:50 PM
30 3wei_SG, cory_ATX, lori_vegas and 27 others
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JennaRN
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Mar 12, 2026 at 12:54 AM#13
chris_chi24 said:
Insulin sensitivity test (HOMA-IR) on glycaemic control — arguably the most important metabolic marker most people aren't tracking: HOMA-IR = (fasting…

I read this differently. The confidence in this thread is running ahead of the evidence, and I would rather the uncertainty were stated than smoothed over because it is unsatisfying.

Last edited: Mar 12, 2026 at 1:54 AM
31 4BiostatsBrad, PeptideSynthNJ, Dr.KarenChen and 28 others
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dan_philly
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Mar 12, 2026 at 8:58 AM#14

One concrete data point for the thread. Say what you would expect to see if you were wrong, before you look. It is a small discipline and it changes what you notice.

Last edited: Mar 12, 2026 at 11:58 AM
32 5Dr.CardioMD, EndoResFellow, PharmacoVig_BOS and 29 others
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mike_mod
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Mar 12, 2026 at 5:01 PM#15

Moderator note: the sourcing question belongs in the vendor section and has been split out. Thread quality here is what the rules are for. Keep it up.

33 6PurityPaulOR, MaxMetOK, MounjBrad and 30 others
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