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ForumsMetabolic Health & DiabetesAdiponectin and leptin changes on GLP-1 therapy — what worked for you? Page 4

Adiponectin and leptin changes on GLP-1 therapy — what worked for you?

bri_stats Mon, Dec 15, 2025 at 5:59 AM 39 replies 1,546 viewsPage 4 of 8
carl_compliance
Member
234
1,123
Nov 2024
Raleigh, NC
Dec 16, 2025 at 11:02 PM#16

From the other side of the consultation, briefly.

Before/after narrative for mental health — one year in:

Before (292 lbs): Winded climbing stairs, chronic back pain, pre-diabetic, on 3 medications, dreaded mirrors, avoided photos, social anxiety about my weight.

After (177 lbs): Run 3 miles regularly, pain-free, A1C normal, down to 1 medication, bought a swimsuit for the first time in a decade, actually enjoy being photographed.

Total weight lost: 92 lbs. Total life gained: immeasurable. This isn't just about weight — it's about reclaiming your identity.

27 0labquiet_amy, emily_PDX, Dr.SleepRoch and 24 others
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marco_milano
Member
345
1,456
Jul 2024
Milan, IT
Dec 17, 2025 at 3:58 AM#17
carl_compliance said:
Before/after narrative for mental health — one year in: Before (292 lbs): Winded climbing stairs, chronic back pain, pre-diabetic, on 3 medications,…

Body image adjustment with mental health: I've lost 78 lbs but when I look in the mirror, I still see my old self sometimes. "Phantom fat" is a real phenomenon.

My therapist specializes in body image issues with weight loss patients. She says it can take 12-18 months for your brain's body map to update. In the meantime: take progress photos (your eyes lie but cameras don't), try on old clothes, and be patient with yourself.

28 1alex_tucson, kevin_tulsa, Dr.PainCLE and 25 others
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LipidDoc_ATL
Senior Member
1,123
5,678
Apr 2024
Atlanta, GA
Dec 17, 2025 at 8:54 AM#18
carl_compliance said:
Before/after narrative for mental health — one year in: Before (292 lbs): Winded climbing stairs, chronic back pain, pre-diabetic, on 3 medications,…

No disagreement, though it depends on where somebody is starting from, and this thread has been assuming a starting point nobody stated.

29 2AttorneyGrant, DebRD_ATL, KristenIndy and 26 others
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TrialNerd_Beth
Senior Member
2,345
11,234
Jan 2024
Bethesda, MD
Dec 17, 2025 at 1:50 PM#19
carl_compliance said:
Before/after narrative for mental health — one year in: Before (292 lbs): Winded climbing stairs, chronic back pain, pre-diabetic, on 3 medications,…

Bookmarking. The distinction being drawn above is the one nobody else makes.

30 3DoseLogDan, SleepFixSam, PurityPaulOR and 27 others
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mike_mod
Moderator
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Nov 2023
New York
Online
Dec 17, 2025 at 6:45 PM#20

Moderator note: leaving this open. It is being argued well and the disagreement is the useful part. Carry on.

Last edited: Dec 17, 2025 at 8:45 PM
2 0PurityPaulOR, MaxMetOK
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