Clinical perspective, offered as context rather than as advice. The honest answer is that the effect is real, the magnitude is contested, and the individual variation is larger than either. Those three things can all be true at once, and most arguments here are two people holding different parts of that.
One thing that is still open after anders_CPH’s answer:
What did you change at the same time, and can you separate the two now?
newstart_MO said:The honest answer is that the effect is real, the magnitude is contested, and the individual variation is larger than either.
Pushing back on newstart_MO here. Not convinced. The evidence being cited is consistent with the conclusion and also consistent with two other conclusions nobody has ruled out.
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Browse GL Biochemnewstart_MO said:The honest answer is that the effect is real, the magnitude is contested, and the individual variation is larger than either.
That is right for the common case. Whether it is right for the case being asked about depends on a detail that has not been given.