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ForumsMetabolic Health & DiabetesHOMA-IR tracking on GLP-1 — looking for input Page 6

HOMA-IR tracking on GLP-1 — looking for input

FDA_TrackerJim Tue, Nov 18, 2025 at 8:10 PM 41 replies 1,975 viewsPage 6 of 9
COA_Karl
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Jan 10, 2026 at 10:15 PM#26
Dr.KarenChen said:
The honest answer is that the effect is real, the magnitude is contested, and the individual variation is larger than either.

There is a second half to this that has not been said yet. It helps to say which part of this you are uncertain about. A precise question gets a precise answer; a general one gets everybody’s favourite anecdote.

48 21matt_MKE, Dr.ReproEndo, lucas_SP_BR and 45 others
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DataDave
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Jan 18, 2026 at 12:14 AM#27

One concrete data point for the thread. For anyone reading later: the numbers in this thread are worth checking against a primary source before you act on them, including mine. Half the figures circulating in this community trace back to a secondary summary that dropped a qualifier.

Last edited: Jan 18, 2026 at 1:14 AM
49 22mike_nyc, VendorMark, COA_Karl and 46 others
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kate.chem
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Jan 25, 2026 at 2:09 AM#28

One thing that is still open after Dr.KarenChen’s answer:

What would you measure differently if you were starting again?

50 23tyler_CSCS, VanRx_Mike, steve_okc and 47 others
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DerekSJ_a1c
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Feb 1, 2026 at 3:59 AM#29
DataDave said:
For anyone reading later: the numbers in this thread are worth checking against a primary source before you act on them, including mine.

Careful with the causal language. Two things moving together in a period when five things changed is not a mechanism, and stating it as one makes the thread less useful to somebody reading it later.

Last edited: Feb 1, 2026 at 8:59 AM
1 24traveltech_sara
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FDA_TrackerJim
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Feb 8, 2026 at 5:46 AM#30

OP back with an update, since a thread like this is useless without one.

Late follow-up. I did not do what was suggested, I did something adjacent, and it worked; posting the difference in case it matters to somebody.

23 21jason_paloalto, Dr.LeslieOBGYN, MikeNYC_runner and 20 others
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