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ForumsMetabolic Health & DiabetesHOMA-IR tracking on GLP-1 — looking for input Page 8

HOMA-IR tracking on GLP-1 — looking for input

FDA_TrackerJim Tue, Nov 18, 2025 at 8:10 PM 41 replies 1,975 viewsPage 8 of 9
mike.trainer_LA
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Mar 22, 2026 at 6:26 AM#36

One thing that is still open after Dr.DermMIA’s answer:

How would you tell the difference between that and the alternative explanation?

Last edited: Mar 22, 2026 at 10:26 AM
29 2Dr.AddMedPHL, newstart_MO, mia_MS2 and 26 others
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DerekSJ_a1c
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Mar 29, 2026 at 6:19 AM#37
BethLabQueen said:
Say what you would expect to see if you were wrong, before you look.

I do not accept the framing. The question has been narrowed to the version that has a tidy answer, and the part that was dropped is the part the OP actually asked about.

30 3Dr.SurgeonPGH, rachel_ABQ, traveltech_sara and 27 others
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VendorMark
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Apr 5, 2026 at 6:07 AM#38
BethLabQueen said:
Say what you would expect to see if you were wrong, before you look.

True, and it depends on a baseline nobody has stated. Without knowing where someone started, the same number can be an excellent result or a disappointing one.

31 4MarkLI_maint, Dr.PeteFamMed, claudia_zurich and 28 others
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stefan_berlin
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Apr 12, 2026 at 5:52 AM#39
BethLabQueen said:
Say what you would expect to see if you were wrong, before you look.

Saving this. It is the first explanation that did not require me to already understand it.

32 5TirzTom, TrialTracker_MD, JennaRN and 29 others
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traveltech_sara
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Apr 19, 2026 at 5:32 AM#40

Adding the clinical framing, because it changes how the question reads. Whatever the answer turns out to be, the method for getting there is the same: state the assumption, do the arithmetic in public, and invite the correction. That is slower than asserting, and it is the only version that survives being wrong.

4 2BenResearch_OR, MikeKY_noInsulin, Dr.RaviCardio and 1 other
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