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ForumsPharmacology & MechanismsReceptor internalization and recycling — anyone have experience? Page 7

Receptor internalization and recycling — anyone have experience?

jennifer_SEA Sat, Apr 26, 2025 at 6:12 AM 36 replies 2,034 viewsPage 7 of 8
tommy_boulder
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Boulder, CO
May 10, 2025 at 1:08 PM#31
jennifer_SEA said:
Closing this out: the trough rather than the peak explains the pattern I was seeing on day six, which I had been blaming on the vial.

Can confirm. Same sequence, different timescale. I had assumed I was the exception until I read this.

18 16paul_denver, TinaHashiRN, robert_kc and 15 others
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nancy_portland
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Portland, ME
May 11, 2025 at 2:34 PM#32
jennifer_SEA said:
Closing this out: the trough rather than the peak explains the pattern I was seeing on day six, which I had been blaming on the vial.

Coming at jennifer_SEA’s question from a different direction. Start from the measurement rather than the conclusion. Almost every disagreement here turns out to be two people measuring different things and comparing the numbers anyway.

Last edited: May 11, 2025 at 3:34 PM
19 17KristenIndy, MarkLI_maint, Dr.PeteFamMed and 16 others
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lucas_SP_BR
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São Paulo, BR
May 12, 2025 at 3:59 PM#33

One concrete data point for the thread. One practical note: write down what you did and when, before you need it. Reconstructing a timeline from memory three months later is how people end up unable to answer the one question that would have resolved it.

Last edited: May 12, 2025 at 5:59 PM
20 18zoe_NC, Dr.ObesityLA, NurseKim_ATL and 17 others
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PharmHunterJen
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May 13, 2025 at 5:24 PM#34

A narrower follow-up, since the general answer is now clear:

How long did you give it before you decided it was working?

Last edited: May 13, 2025 at 11:24 PM
21 19Dr.PainCLE, mike_mealprep, NicoleRaleigh and 18 others
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TinaHashiRN
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Raleigh, NC
May 14, 2025 at 6:48 PM#35
lucas_SP_BR said:
One practical note: write down what you did and when, before you need it.

This is where I part company with the consensus forming above. The counter-case has not been addressed. Somebody upthread described the situation that does not fit, and the thread moved on rather than engaging with it, which is the failure mode this board is supposed to avoid.

Last edited: May 15, 2025 at 12:48 AM
22 20MikeNYC_runner and 19 others
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