🍪 CompoundTalk uses cookies to improve your experience, analyze traffic, and personalize content. By continuing to use this site, you agree to our Cookie Policy.
Evidence-based GLP-1 & peptide discussion since 2023
ForumsPublic SquareMuscle protein synthesis rates on GLP-1 — leucine threshold discussion Page 4

Muscle protein synthesis rates on GLP-1 — leucine threshold discussion

ChrisMacros Mon, May 25, 2026 at 8:37 AM 21 replies 460 viewsPage 4 of 5
Dr.ObesityLA
VIP Member
3,567
19,876
Dec 2023
Los Angeles, CA
May 28, 2026 at 6:21 AM#16

Clinical perspective, offered as context rather than as advice. Take it one variable at a time. Almost every unanswerable question in these threads is unanswerable because three things changed in the same fortnight, and no amount of subsequent argument can untangle them after the fact.

47 20zoe_NC, Dr.ObesityLA, NurseKim_ATL and 44 others
Reply Quote Save Share Report
Dr.RaviCardio
VIP Member
2,890
15,678
Jan 2024
New York, NY
May 28, 2026 at 5:06 PM#17

One concrete data point for the thread. The boring version of this is the one that works, and the boring version is: measure a baseline, change one variable, wait, measure again under the same conditions. Nobody wants that answer and it is still the answer.

Last edited: May 28, 2026 at 6:06 PM
48 21anna.melb_AU, mark_tokyo, hans_munich and 45 others
Reply Quote Save Share Report
sarah_TO
Member
278
1,234
Sep 2024
Toronto, CA
May 29, 2026 at 3:52 AM#18

A narrower follow-up, since the general answer is now clear:

Whether resistance training and protein change the ratio or only the absolute amount?

49 22GraceAZ_72, carl_compliance, DanielChem_CHI and 46 others
Reply Quote Save Share Report

PeptideMeter — Independent Peptide Analytics

Community-driven peptide testing and vendor rating platform. Transparent results. Unbiased analysis. Trusted by thousands.

View Results
EndoResFellow
Member
456
2,345
Sep 2024
Baltimore, MD
May 29, 2026 at 2:39 PM#19
Dr.RaviCardio said:
The boring version of this is the one that works, and the boring version is: measure a baseline, change one variable, wait, measure again under the…

Worth saying that the confident version of this is more useful to the person writing it than to the person reading it.

50 23NurseKim_ATL, paul_denver, TinaHashiRN and 47 others
Reply Quote Save Share Report
mike_mod
Moderator
7,234
19,823
Nov 2023
New York
Online
May 30, 2026 at 1:25 AM#20

Moderator note: two posts asking for a source have been merged into one. Please search the thread before asking again. Thread quality here is what the rules are for. Keep it up.

22 20PurityPaulOR, MaxMetOK, MounjBrad and 19 others
Reply Quote Save Share Report

Similar Threads

SELECT trial 4-year follow-up data released — sustained MACE reduction16 replies
GLP-1 receptor agonists and thyroid C-cell concerns — evidence review19 replies
Is there a ceiling effect for GLP-1-mediated weight loss?20 replies
Comparative pharmacokinetics: semaglutide vs tirzepatide vs retatrutide6 replies
My 18-month semaglutide journey — comprehensive data log20 replies
ForumsNewTrendingMembersAccount

Log In

Forgot password?
No account? Register