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ForumsOral GLP-1 AgonistsOral semaglutide 50mg (Rybelsus HD) — 12 month update Page 9

Oral semaglutide 50mg (Rybelsus HD) — 12 month update

LibrarianMeg Thu, May 30, 2024 at 6:09 AM 44 replies 2,300 viewsPage 9 of 9
MikeFit_NJ
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Aug 10, 2024 at 9:53 PM#41

One thing that is still open after jim_asheville’s answer:

What the dose-response curve actually looks like above 1.7mg, because the trial means hide how few people account for the extra loss?

16 16LeilaHI, marcus_mpls, DeniseRN_TPA and 13 others
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mark_tokyo
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Aug 14, 2024 at 3:27 AM#42
jason_paloalto said:
Worth stating the units and the reference range whenever you post a number here.

Filing a mild objection. Mild because I might be wrong; an objection because nobody has addressed the case that does not fit. Pushing back on the anecdote-stacking. Twenty people reporting the same thing is twenty samples from the same self-selected pool, not twenty independent confirmations.

15 15bri_stats, pete_manc_UK, anna.melb_AU and 12 others
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mike_mod
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Aug 17, 2024 at 9:03 AM#43

Moderator note: good thread. Keeping it here rather than moving it, because the question is general enough to be useful. No action needed from anybody.

Last edited: Aug 17, 2024 at 11:03 AM
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NurseAsh_DET
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Aug 20, 2024 at 2:40 PM#44
jason_paloalto said:
Worth stating the units and the reference range whenever you post a number here.

That reframing is the part I needed.

Last edited: Aug 20, 2024 at 8:40 PM
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jim_asheville
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Aug 23, 2024 at 8:19 PM#45

Adding the clinical framing, because it changes how the question reads. The mechanism and the magnitude are separate questions. Agreeing that something happens says nothing about whether it happens enough to act on.

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