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ForumsPublic SquareNovo Nordisk CagriSema Phase 3 results — need advice Page 4

Novo Nordisk CagriSema Phase 3 results — need advice

mike_mod Tue, Nov 18, 2025 at 8:31 PM 43 replies 1,982 viewsPage 4 of 9
claudia_zurich
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Nov 20, 2025 at 3:43 PM#16

Adding the clinical framing, because it changes how the question reads. Whatever the answer turns out to be, the method for getting there is the same: state the assumption, do the arithmetic in public, and invite the correction. That is slower than asserting, and it is the only version that survives being wrong.

Last edited: Nov 20, 2025 at 9:43 PM
50 0emma_london, tammy_FL, Dr.LipidDallas and 47 others
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GraceAZ_72
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Nov 20, 2025 at 9:56 PM#17
Dr.PeteFamMed said:
Worth stating the units and the reference range whenever you post a number here.

Agreed, and one caution: a single measurement is not a measurement. Anything that moves day to day needs a trend before it means anything at all.

Correct me if the detail matters more than I have assumed.

Last edited: Nov 21, 2025 at 1:56 AM
49 24CryptoCarl, MariaRD, AussieAnna and 46 others
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emma_london
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Nov 21, 2025 at 4:09 AM#18
Dr.PeteFamMed said:
Worth stating the units and the reference range whenever you post a number here.

Bookmarking. The distinction being drawn above is the one nobody else makes. Adding it to my notes with a link back to this thread.

Last edited: Nov 21, 2025 at 10:09 AM
48 23TomFromTexas, mike.trainer_LA, sarah_nash92 and 45 others
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Dr.MetabolicMD
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Nov 21, 2025 at 10:22 AM#19

Adding the clinical framing, because it changes how the question reads. The honest answer is that the effect is real, the magnitude is contested, and the individual variation is larger than either. Those three things can all be true at once, and most arguments here are two people holding different parts of that.

47 22Dr.ObesityMed, HealthEcon_DC, PedsEndoPhilly and 44 others
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lucas_SP_BR
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Nov 21, 2025 at 4:35 PM#20

Moderator note: leaving this open. It is being argued well and the disagreement is the useful part. Tagging this one for the weekly digest.

25 0tampaLisa73, KarenAZ_mom, zoe_NC and 22 others
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