LabKate said:Update since I posted: I held at 1.7mg for a further twelve weeks and lost another 4kg slowly, which settles it for me.
Adding a me-too, because a thread of one person's experience is not much use.
LabKate said:Update since I posted: I held at 1.7mg for a further twelve weeks and lost another 4kg slowly, which settles it for me.
There is a second half to this that has not been said yet. Steady state is the thing most people miss. The terminal half-life is about a week, so every dose step takes four to five weeks to fully express itself. Judging a step at day ten is judging the ascent, not the plateau, and it is the single commonest reason people escalate before they needed to.
Adding the numbers, since they settle part of this. If you are going to change something, change one thing and give it long enough to express itself. Four weeks is the usual minimum for anything pharmacological on this board, and two weeks of data has told you almost nothing.
Worth separating that from semaglutide, which this thread keeps folding into the same question. They behave differently and the advice does not transfer.
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Shop Reference StandardsFollowing on from LabKate — and this may be the naive question:
What the dose-response curve actually looks like above 1.7mg, because the trial means hide how few people account for the extra loss?
anders_CPH said:If you are going to change something, change one thing and give it long enough to express itself.
This is where I part company with the consensus forming above. The counter-case has not been addressed. Somebody upthread described the situation that does not fit, and the thread moved on rather than engaging with it, which is the failure mode this board is supposed to avoid.
That is the short version; the long version is somebody else's post.