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ForumsPublic SquareAmylin co-agonism: CagriSema REDEFINE results and implications — 6 month update Page 6

Amylin co-agonism: CagriSema REDEFINE results and implications — 6 month update

Dr.SportsMedIN Wed, Apr 16, 2025 at 10:44 AM 31 replies 1,645 viewsPage 6 of 7
Dr.PeteFamMed
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Apr 22, 2025 at 12:31 AM#26

Adding the numbers, since they settle part of this. Practical: whatever you change, write down the date and the reason. In three months the reason is what you will have forgotten, and the reason is what makes the record worth having.

Last edited: Apr 22, 2025 at 1:31 AM
11 9hyun_seoul, jim_asheville, matt_MKE and 8 others
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Dr.RenalNash
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Apr 22, 2025 at 2:35 PM#27

A narrower follow-up, since the general answer is now clear:

What did you change at the same time, and can you separate the two now?

Last edited: Apr 22, 2025 at 7:35 PM
12 10pam_stl, wei_SG, cory_ATX and 9 others
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adam_van
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Vancouver, CA
Apr 23, 2025 at 4:39 AM#28
Dr.PeteFamMed said:
Practical: whatever you change, write down the date and the reason.

Pushing back on Dr.PeteFamMed here. I would resist the confidence. Half of what this board was certain about two years ago has since been quietly dropped, and nobody went back to correct the threads.

13 11LindaRN_retired, tommy_boulder, hyun_seoul and 10 others
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TrialTracker_MD
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Jan 2024
Maryland
Apr 23, 2025 at 6:44 PM#29
Dr.PeteFamMed said:
Practical: whatever you change, write down the date and the reason.

Agreed, and the size of the effect matters as much as its existence. Something real and small gets treated here as though it were real and decisive.

14 12Dr.PulmRoch, maya_sedona, stefan_berlin and 11 others
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Dr.SportsMedIN
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Indianapolis, IN
Apr 24, 2025 at 8:49 AM#30

Reporting back.

Closing this out: the trough rather than the peak explains the pattern I was seeing on day six, which I had been blaming on the vial.

36 9rachel_ABQ, traveltech_sara, AttorneyGrant and 33 others
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