🍪 CompoundTalk uses cookies to improve your experience, analyze traffic, and personalize content. By continuing to use this site, you agree to our Cookie Policy.
Evidence-based GLP-1 & peptide discussion since 2023
ForumsCompounding & FormulationBacteriostatic water sourcing and sterility considerations — July 2024 Page 2

Bacteriostatic water sourcing and sterility considerations — July 2024

Dr.GastroMayo Tue, Dec 17, 2024 at 10:11 AM 48 replies 2,414 viewsPage 2 of 10
TrialTracker_MD
Senior Member
2,345
15,678
Jan 2024
Maryland
Dec 18, 2024 at 4:35 AM#6
Dr.NateNeph said:
Dead space is the answer to the missing dose.

I am going to disagree with reconstituting low as a general rule. More diluent, more punctures, more in-use days at room temperature, and the stability trade-off is real. Precision is not the only variable being optimised.

Happy to go further on any of that.

Last edited: Dec 18, 2024 at 9:35 AM
3 6Dr.EM_Chicago, pete_RVA, CarlaRPh_TPA
Reply Quote Save Share Report
Dr.AddMedPHL
Senior Member
1,234
6,234
Mar 2024
Philadelphia, PA
Dec 18, 2024 at 11:53 AM#7

The figures, for anyone assembling their own picture. Red flags, in rough order of how much they should worry you: no verifiable address, no batch numbers, prices far under market, vendor-commissioned tests only, pressure toward irreversible payment, and shipping with no temperature control.

4 7sarah_nash92, FitDadDave, RunnerRach and 1 other
Reply Quote Save Share Report
sarah_TO
Member
278
1,234
Sep 2024
Toronto, CA
Dec 18, 2024 at 7:11 PM#8
TrialTracker_MD said:
I am going to disagree with reconstituting low as a general rule.

There is a second half to this that has not been said yet. Prices dramatically below market are the strongest single signal, and the reason is arithmetic rather than suspicion. Synthesis, testing, and cold-chain shipping have floors. A price well under the floor means something was skipped, and the two things that get skipped are testing and content.

5 8GraceAZ_72, carl_compliance, DanielChem_CHI and 2 others
Reply Quote Save Share Report

Sigma-Aldrich — Research-Grade Standards

Certified reference materials, analytical reagents, and research-grade standards for peptide verification. Trusted by laboratories worldwide.

Shop Reference Standards
TomFromTexas
Member
645
2,890
May 2024
Austin, TX
Dec 19, 2024 at 2:29 AM#9

Following on from jason_sac26 — and this may be the naive question:

How to check the arithmetic without trusting a website calculator, since three calculators gave me three answers?

6 9PeptideSynthNJ, Dr.KarenChen, Dr.NateNeph and 3 others
Reply Quote Save Share Report
Dr.GastroMayo
VIP Member
2,345
13,456
Jan 2024
Mayo Clinic, MN
Dec 20, 2024 at 1:30 PM#10

Reporting back.

Resolved. I wrote mg, ml and mg/ml on the vial in marker and did the division in that order, and the two of us now get the same number every time.

26 1InsuranceTom, WendyG_ATL, SaraMom3 and 23 others
Reply Quote Save Share Report

Similar Threads

503A vs 503B compounding — regulatory framework explained4 replies
Compounded semaglutide stability: accelerated degradation study results6 replies
Lyophilized vs liquid peptides — stability and bioavailability comparison18 replies
Bacteriostatic water sourcing and sterility considerations8 replies
State-by-state compounding pharmacy regulations — 2026 map8 replies
ForumsNewTrendingMembersAccount

Log In

Forgot password?
No account? Register