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ForumsCompounding & FormulationBacteriostatic water sourcing and sterility considerations — July 2024 Page 3

Bacteriostatic water sourcing and sterility considerations — July 2024

Dr.GastroMayo Tue, Dec 17, 2024 at 10:11 AM 48 replies 2,414 viewsPage 3 of 10
LibrarianMeg
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Dec 22, 2024 at 2:11 PM#11
sarah_TO said:
Prices dramatically below market are the strongest single signal, and the reason is arithmetic rather than suspicion.

Right, and one flattering data point from a group buy is not consistency. Consistency means separate batches, separately commissioned, over months.

25 0Dr.NateNeph, PharmD_Rodriguez, julia.endo and 22 others
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NauseaFreeNow
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Dec 24, 2024 at 2:53 PM#12
jason_sac26 said:
Agreed, and it is worth saying that rounding to the nearest whole unit is usually acceptable at maintenance doses and is not acceptable at the bottom…

Saving this. It is the first explanation that did not require me to already understand it. I will report back once I have actually tried it.

Last edited: Dec 24, 2024 at 6:53 PM
24 24maya_sedona, stefan_berlin, Dr.EM_Chicago and 21 others
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MeganSA_TX
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Dec 26, 2024 at 3:36 PM#13
sarah_TO said:
Prices dramatically below market are the strongest single signal, and the reason is arithmetic rather than suspicion.

I disagree that testing history is decisive. It tells you what a supplier did when they were being watched. Continuity of behaviour under stress — a late shipment, a failed test, a complaint — is more predictive than any run of good results.

Worth separating that from vendor vetting, which this thread keeps folding into the same question. They behave differently and the advice does not transfer.

23 23JessicaM_2024, TomFromTexas, mike.trainer_LA and 20 others
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hank_denver
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Sep 2024
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Dec 28, 2024 at 4:20 PM#14
Dr.GastroMayo said:
Two of us with identical vials and identical diluent arrived at different unit counts, which means one of us has a conceptual error rather than a…

For anyone reconstituting dosing arithmetic peptides: the water-to-powder ratio determines your concentration. Here's my reference:

Vial SizeBAC WaterConcentration0.25mg Dose
5mg2mL2.5mg/mL10 units
5mg2.5mL2mg/mL12.5 units
10mg2mL5mg/mL5 units
10mg3mL3.33mg/mL7.5 units

More water = easier to measure small doses but vial runs out faster. Find the balance that works for your dose.

22 22fiona_VT, denise_HTX, raj_cambridge and 19 others
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mike_mod
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Dec 30, 2024 at 5:05 PM#15

Moderator note: a post naming a supplier has been edited. Discuss suppliers in the review sections, not here. Report rather than reply if it drifts again.

21 21PurityPaulOR, MaxMetOK, MounjBrad and 18 others
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