From the other side of the consultation, briefly.

Continuous metabolic monitoring dashboard for cardiovascular risk — I track everything in a spreadsheet and here's the month-over-month trend for my key markers:

Weight: consistent downtrend, -2.2 lbs/week average
Fasting glucose (finger stick): stable at 87 mg/dL
Blood pressure (home): 117/73 average
Resting heart rate: 67 bpm (down from 83)
Waist circumference: down 17 inches total

The resting heart rate improvement correlates with cardiovascular fitness gains. Everything is moving in the right direction.

BiostatsBrad said:

Mendelian randomization evidence supporting GLP-1 pathway modulation for cardiovascular risk: genetic variants in the GLP1R gene region associated…

This answered a question I did not know how to ask. I will report back once I have actually tried it.

Clinical perspective, offered as context rather than as advice.

6 month update on cardiovascular risk: down 37 lbs, off blood pressure meds, A1C normalized. Genuinely life-changing.

KevinCompounds said:

6 month update on cardiovascular risk: down 37 lbs, off blood pressure meds, A1C normalized.

This is my experience too, for whatever a second data point is worth. Posting only so the count is not one.

Moderator note: a couple of off-topic posts removed. Carry on.