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ForumsCardiovascular OutcomesSOUL trial preliminary data — November 2025 Page 5

SOUL trial preliminary data — November 2025

JenMemphis Sun, Mar 16, 2025 at 2:50 AM 51 replies 2,130 viewsPage 5 of 11
NurseKim_ATL
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Mar 21, 2025 at 1:49 AM#21

Clinical perspective, offered as context rather than as advice. If two explanations both fit, the useful question is which one predicts something the other does not. That is answerable; arguing about which sounds more plausible is not.

Last edited: Mar 21, 2025 at 6:49 AM
4 2denise_HTX, raj_cambridge, ingrid_STO and 1 other
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SkepticalSean
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Mar 21, 2025 at 9:45 PM#22
NurseKim_ATL said:
If two explanations both fit, the useful question is which one predicts something the other does not.

Same pattern here, and in the same order. The detail I would add is minor and it is already implied above.

5 3paige_pharma, emma_london, tammy_FL and 2 others
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PharmHunterJen
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Mar 22, 2025 at 5:40 PM#23
NurseKim_ATL said:
If two explanations both fit, the useful question is which one predicts something the other does not.

Adding the part of the answer the thread has not reached. Order of operations matters more than any single choice here: establish a baseline, change one thing, wait long enough for it to express itself, then measure again under the same conditions.

Last edited: Mar 22, 2025 at 11:40 PM
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josh_phd_bmore
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Mar 23, 2025 at 1:35 PM#24

The figures, for anyone assembling their own picture. One habit that pays for itself: post the method alongside the number. A figure without its method cannot be checked, and an unchecked figure is how this community accumulates folklore.

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TomFromTexas
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Mar 24, 2025 at 9:29 AM#25

Following on from NurseKim_ATL — and this may be the naive question:

How long did you give it before you decided it was working?

8 6BiostatsBrad, PeptideSynthNJ, Dr.KarenChen and 5 others
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