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Evidence-based GLP-1 & peptide discussion since 2023
ForumsLab Results & BiomarkersVitamin B12 monitoring — 6 month update

Vitamin B12 monitoring — 6 month update

emma_london Tue, Mar 10, 2026 at 1:40 PM 8 replies 769 viewsPage 1 of 2
emma_london
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London, UK
Mar 10, 2026 at 1:40 PM#1

I started taking a multivitamin as insurance and then found out that two of the things I was actually short of were the two it barely contains.

Cheap and worth having: ferritin, B12, vitamin D. Everything else on the deficiency list is adequately covered by a standard multivitamin at ordinary doses.

What I am after is which deficiencies actually show up when intake drops this far, and which are worth testing rather than supplementing blind.

I have searched first, so if this is covered somewhere point me at it and I will read it.

48 1sarah_nash92, FitDadDave, RunnerRach and 45 others
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NurseKim_ATL
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Atlanta, GA
Mar 10, 2026 at 2:02 PM#2
emma_london said:
I started taking a multivitamin as insurance and then found out that two of the things I was actually short of were the two it barely contains.

Iron studies on micronutrients — important especially for women:

MarkerBaselineMonth 6After Supplementation
Ferritin661956
Iron966179
TIBC321391331
Transferrin Sat33%16%30%

My ferritin cratered at month 6 from reduced dietary intake. Iron bisglycinate 36mg with vitamin C brought it back up. Don't wait for anemia symptoms — test proactively.

Last edited: Mar 10, 2026 at 7:02 PM
49 2raj_cambridge, ingrid_STO, pete_nash and 46 others
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PedsEndoPhilly
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Mar 10, 2026 at 2:24 PM#3
NurseKim_ATL said:
Iron studies on micronutrients — important especially for women: Marker Baseline Month 6 After Supplementation Ferritin 66 19 56 Iron 96 61 79 TIBC…

Vitamin D levels and micronutrients: an often-overlooked connection. Obese individuals store vitamin D in adipose tissue, making it less bioavailable. As you lose fat, vitamin D can actually increase WITHOUT supplementation.

My trajectory: Baseline 18 ng/mL → Month 6 (with supplement) 42 ng/mL → Month 12 48 ng/mL. Target is 40-60 ng/mL. Adequate vitamin D supports immune function, bone health, and mood — all relevant during weight loss.

50 3jason_paloalto, Dr.LeslieOBGYN, MikeNYC_runner and 47 others
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B12Beth
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Mar 10, 2026 at 2:46 PM#4
emma_london said:
I started taking a multivitamin as insurance and then found out that two of the things I was actually short of were the two it barely contains.

Second this. The detail I would add is minor and it is already implied above.

Last edited: Mar 10, 2026 at 5:46 PM
1 4marco_milano
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pete_nash
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Nashville, TN
Mar 10, 2026 at 4:46 PM#5

Adding the clinical framing, because it changes how the question reads.

Blood count monitoring for micronutrients: my doctor noticed my MCV (mean corpuscular volume) trending up at month 6: 88 → 98 fL. This flagged potential B12 or folate deficiency.

Sure enough, B12 had dropped from 620 to 340 pg/mL. Started B12 injections monthly and MCV normalized within 2 months. GLP-1 agonists can impair B12 absorption — this is a real clinical concern that deserves routine monitoring.

2 5sarah.morrison, NeuroNate
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