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ForumsLab Results & BiomarkersSHBG changes during weight loss on GLP-1 — July 2024 Page 2

SHBG changes during weight loss on GLP-1 — July 2024

NicoleRaleigh Thu, Mar 5, 2026 at 6:29 PM 10 replies 790 viewsPage 2 of 2
PharmacoVig_BOS
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Mar 5, 2026 at 7:53 PM#6
LibrarianMeg said:
Hormone panel changes on the hormone panel — relevant for anyone curious about endocrine effects: Testosterone: increased 35% (weight loss reduces…

I am going to disagree with the direction of travel here. The thread has converged on the tidiest answer rather than the best-supported one, and those are not the same thing.

Last edited: Mar 5, 2026 at 10:53 PM
48 1amsterdam_pete, LondonLisa, mike_nyc and 45 others
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lisa_labSD
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Mar 5, 2026 at 8:26 PM#7

One concrete data point for the thread. Give anything pharmacological four weeks before you judge it, and give anything measured weekly a four-point rolling average before you call it a trend.

Last edited: Mar 5, 2026 at 11:26 PM
49 2maya_sedona, stefan_berlin, Dr.EM_Chicago and 46 others
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sean_dublin
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Mar 5, 2026 at 8:59 PM#8
PharmacoVig_BOS said:
I am going to disagree with the direction of travel here.

There is a second half to this that has not been said yet. It helps to ask what evidence would change your mind before you look at any. If nothing would, the discussion is not about evidence, and it is better to say so early than to spend nine posts discovering it.

50 3gary_naperville, sean_dublin, hannah_MT and 47 others
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TinaHashiRN
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Mar 5, 2026 at 9:32 PM#9

A narrower follow-up, since the general answer is now clear:

How would you tell the difference between that and the alternative explanation?

Last edited: Mar 6, 2026 at 3:32 AM
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NicoleRaleigh
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Mar 6, 2026 at 12:09 AM#10

OP back with an update, since a thread like this is useless without one.

Coming back a few months on. It held. Nothing dramatic to report, which is the report.

Last edited: Mar 6, 2026 at 1:09 AM
21 19mike_nyc, VendorMark, COA_Karl and 18 others
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