One thing that is still open after claudia_zurich’s answer:

What did you change at the same time, and can you separate the two now?

BiostatsBrad said:

If you are going to change something, change one thing and give it long enough to express itself.

I read this differently. The confidence in this thread is running ahead of the evidence, and I would rather the uncertainty were stated than smoothed over because it is unsatisfying.

Correct me if the detail matters more than I have assumed.

BiostatsBrad said:

If you are going to change something, change one thing and give it long enough to express itself.

True, though the ladder is longer and that is not a neutral detail — six dose steps means six opportunities to stall on the way up, and plenty of people never reach the dose the headline number came from.

BiostatsBrad said:

If you are going to change something, change one thing and give it long enough to express itself.

This is exactly what I could not find anywhere else. Printing the relevant bit and taking it with me.

Closing the loop on my own question.

I stayed at 10mg. Another six months, another 7kg, no new side effects, and my reading of the dose-response says the last two steps were never going to be worth what they cost me.