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Evidence-based GLP-1 & peptide discussion since 2023
ForumsCardiovascular OutcomesHeart rate increase on GLP-1 — November 2025 Page 7

Heart rate increase on GLP-1 — November 2025

Dr.ObesityMed Thu, May 30, 2024 at 5:58 AM 31 replies 2,498 viewsPage 7 of 7
ingrid_STO
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Jun 9, 2024 at 2:16 PM#31
bri_stats said:
Mendelian randomization evidence supporting GLP-1 pathway modulation for cardiovascular risk: genetic variants in the GLP1R gene region associated…

That reframing is the part I needed. Sending this to two other people who asked me the same thing last week.

30 3VendorMark, COA_Karl, MikeFit_NJ and 27 others
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Dr.EndoIndy
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Jun 10, 2024 at 8:24 AM#32

Clinical perspective, offered as context rather than as advice. It helps to ask what evidence would change your mind before you look at any. If nothing would, the discussion is not about evidence, and it is better to say so early than to spend nine posts discovering it.

That is the short version; the long version is somebody else's post.

31 4LeilaHI, marcus_mpls, DeniseRN_TPA and 28 others
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LibrarianMeg
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Jun 11, 2024 at 2:32 AM#33
Dr.EndoIndy said:
It helps to ask what evidence would change your mind before you look at any.

Same pattern here, and in the same order. Posting only so the count is not one.

Last edited: Jun 11, 2024 at 4:32 AM
32 5julia.endo, JessicaM_2024, TomFromTexas and 29 others
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patPC_UT
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Jun 11, 2024 at 8:39 PM#34
Dr.EndoIndy said:
It helps to ask what evidence would change your mind before you look at any.

Adding the part of the answer the thread has not reached. It is worth asking what the claim would look like if it were false. If nothing would look different, it is not a claim about the world and no amount of discussion will settle it.

Last edited: Jun 12, 2024 at 1:39 AM
33 6JessicaM_2024, TomFromTexas, mike.trainer_LA and 30 others
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josh_phd_bmore
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Jun 12, 2024 at 2:46 PM#35

The figures, for anyone assembling their own picture. Worth stating the units and the reference range whenever you post a number here. A large fraction of the apparent disagreement in these threads is two people using different units and both being right.

Last edited: Jun 12, 2024 at 4:46 PM
34 7tampaLisa73, KarenAZ_mom, zoe_NC and 31 others
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