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Evidence-based GLP-1 & peptide discussion since 2023
ForumsLab Results & BiomarkersKidney function on semaglutide — my results so far Page 6

Kidney function on semaglutide — my results so far

CanadaChris Tue, Nov 18, 2025 at 2:35 AM 34 replies 1,630 viewsPage 6 of 7
tommy_boulder
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Feb 11, 2026 at 10:48 AM#26
lisa_labSD said:
The useful move here is to separate what is established from what is widely repeated.

There is a second half to this that has not been said yet. It helps to say which part of this you are uncertain about. A precise question gets a precise answer; a general one gets everybody’s favourite anecdote.

If somebody has the primary source to hand I would rather cite it than paraphrase it.

46 19paul_denver, TinaHashiRN, robert_kc and 43 others
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kate.chem
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Feb 22, 2026 at 6:42 PM#27

One concrete data point for the thread. Give anything pharmacological four weeks before you judge it, and give anything measured weekly a four-point rolling average before you call it a trend.

Ask again with the specifics and you will get a better answer than this one.

47 20VanRx_Mike, steve_okc, dave_SLC and 44 others
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tane_welly
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Mar 6, 2026 at 2:28 AM#28

One thing that is still open after lisa_labSD’s answer:

Whether anyone has held at a sub-maximal dose long term and kept the result, or whether the maintenance data only exists at 2.4mg?

48 21DanielChem_CHI, marco_milano, pam_columbus and 45 others
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lori_vegas
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Mar 17, 2026 at 10:09 AM#29
kate.chem said:
Give anything pharmacological four weeks before you judge it, and give anything measured weekly a four-point rolling average before you call it a…

Careful with the causal language. Two things moving together in a period when five things changed is not a mechanism, and stating it as one makes the thread less useful to somebody reading it later.

49 22tane_welly, Dr.PathRoch, mona_PHX and 46 others
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CanadaChris
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Mar 28, 2026 at 5:42 PM#30

OP back with an update, since a thread like this is useless without one.

Update since I posted: I held at 1.7mg for a further twelve weeks and lost another 4kg slowly, which settles it for me. I was escalating because the number was available, not because I had stopped responding.

21 19lori_vegas, Dr.PulmRoch, maya_sedona and 18 others
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