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Evidence-based GLP-1 & peptide discussion since 2023
ForumsLab Results & BiomarkersVitamin B12 monitoring — what worked for you? Page 2

Vitamin B12 monitoring — what worked for you?

bri_stats Fri, Sep 26, 2025 at 8:27 AM 9 replies 1,237 viewsPage 2 of 2
Dr.AddMedPHL
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Sep 26, 2025 at 10:58 AM#6
PharmacoVig_BOS said:
Iron studies on micronutrients — important especially for women: Marker Baseline Month 6 After Supplementation Ferritin 70 23 55 Iron 100 60 83 TIBC…

Blood count monitoring for micronutrients: my doctor noticed my MCV (mean corpuscular volume) trending up at month 6: 91 → 97 fL. This flagged potential B12 or folate deficiency.

Sure enough, B12 had dropped from 620 to 340 pg/mL. Started B12 injections monthly and MCV normalized within 2 months. GLP-1 agonists can impair B12 absorption — this is a real clinical concern that deserves routine monitoring.

41 11FitDadDave, RunnerRach, TrialNerd_Beth and 38 others
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Dr.PulmRoch
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Jun 2024
Rochester, MN
Sep 26, 2025 at 11:57 AM#7

Adding the numbers, since they settle part of this. Say what you would expect to see if you were wrong, before you look. It is a small discipline and it changes what you notice.

Ask again with the specifics and you will get a better answer than this one.

40 10traveltech_sara, AttorneyGrant, DebRD_ATL and 37 others
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TrialNerd_Beth
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Bethesda, MD
Sep 26, 2025 at 12:56 PM#8
Dr.AddMedPHL said:
Blood count monitoring for micronutrients: my doctor noticed my MCV (mean corpuscular volume) trending up at month 6: 91 → 97 fL.

Coming at Dr.AddMedPHL’s question from a different direction. Most of what circulates confidently in this community traces back to one summary of one study, and the qualifier was dropped somewhere in the third retelling.

That is the short version; the long version is somebody else's post.

Last edited: Sep 26, 2025 at 4:56 PM
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adam_van
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Nov 2024
Vancouver, CA
Sep 26, 2025 at 1:55 PM#9

One thing that is still open after JakeBK_lifts’s answer:

How long did you give it before you decided it was working?

38 8tommy_boulder, hyun_seoul, jim_asheville and 35 others
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bri_stats
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May 2024
Seattle, WA
Sep 26, 2025 at 6:41 PM#10

Reporting back.

Update — I was wrong in the opening post, specifically about the direction. Correcting it here rather than editing it away.

50 23julia.endo, JessicaM_2024, TomFromTexas and 47 others
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