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Evidence-based GLP-1 & peptide discussion since 2023
ForumsLab Results & BiomarkersCholesterol dropped 80 points and my doc is shook — anyone have experience? Page 2

Cholesterol dropped 80 points and my doc is shook — anyone have experience?

nancy_portland Wed, Jul 2, 2025 at 9:52 AM 32 replies 1,521 viewsPage 2 of 7
dan_philly
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Philadelphia, PA
Jul 3, 2025 at 1:35 AM#6
nancy_portland said:
ApoB is the more informative number and it is cheap.

Tracking labs for the lipid panel — here's the panel I get every 3 months and why:

  • CMP: glucose, electrolytes, kidney function, liver enzymes
  • Lipid panel: total cholesterol, LDL, HDL, triglycerides
  • A1C: 3-month glucose average
  • hsCRP: inflammatory marker
  • CBC: blood counts, anemia screening
  • B12, folate, iron: nutritional deficiency screening
  • TSH, free T4: thyroid monitoring
  • Lipase: pancreatic safety check

Total cost with insurance: about $38 copay. Without insurance, request cash-pay pricing from Quest/Labcorp — usually $173.

Last edited: Jul 3, 2025 at 4:35 AM
48 18DadBodDave, AmyNC_wife, SkepticalSean and 45 others
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paige_pharma
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Sep 2024
Omaha, NE
Jul 3, 2025 at 7:49 AM#7

One thing that is still open after PharmHunterJen’s answer:

What did you change at the same time, and can you separate the two now?

Last edited: Jul 3, 2025 at 8:49 AM
47 17Dr.SurgeonPGH, rachel_ABQ, traveltech_sara and 44 others
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Dr.DermMIA
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Miami, FL
Jul 3, 2025 at 2:03 PM#8
dan_philly said:
Tracking labs for the lipid panel — here's the panel I get every 3 months and why: CMP: glucose, electrolytes, kidney function, liver enzymes Lipid…

Advanced lipoprotein testing on the lipid panel — going beyond standard lipid panel:

MarkerBaselineMonth 8Clinical Meaning
LDL-P1663963Particle count (more precise than LDL-C)
Small dense LDL63%35%Atherogenic pattern
Remnant cholesterol4317Triglyceride-rich lipoproteins
oxLDL6841Oxidative stress marker

The shift from small dense to large buoyant LDL is particularly important — it represents a fundamental change in the atherogenic profile.

46 16A1cHero_PHX, Dr.RenalNash, LipidDoc_ATL and 43 others
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nancy_portland
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Aug 2024
Portland, ME
Jul 3, 2025 at 8:17 PM#9
dan_philly said:
Tracking labs for the lipid panel — here's the panel I get every 3 months and why: CMP: glucose, electrolytes, kidney function, liver enzymes Lipid…

Comprehensive lipid panel update relevant to the lipid panel:

MarkerBaseline6 Months12 MonthsReference
Total Cholesterol230195175<200
LDL14513095<100
HDL384552>40
Triglycerides25018595<150
LDL-P16901140940<1000

The triglyceride drop is the most impressive. My cardiologist reduced my statin dose based on these results.

45 15Dr.PeteFamMed, claudia_zurich, nancy_portland and 42 others
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BethLabQueen
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Virginia
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Jul 5, 2025 at 2:14 AM#10
Dr.DermMIA said:
Advanced lipoprotein testing on the lipid panel — going beyond standard lipid panel: Marker Baseline Month 8 Clinical Meaning LDL-P 1663 963 Particle…

Correct, and worth adding that it is reversible. Nothing being described here is a one-way door, which changes how cautious it is reasonable to be.

33 6wei_SG, cory_ATX, lori_vegas and 30 others
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