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Evidence-based GLP-1 & peptide discussion since 2023
ForumsLab Results & BiomarkersOptimal lab testing frequency on GLP-1 — 6 month update

Optimal lab testing frequency on GLP-1 — 6 month update

tane_welly Sun, May 25, 2025 at 1:13 PM 10 replies 1,470 viewsPage 1 of 2
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tane_welly
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Wellington, NZ
May 25, 2025 at 1:13 PM#1

I got a full panel before starting and a repeat at three months, and the second one is more useful than the first purely because I now have something to compare against.

What I am trying to establish is what actually belongs on a baseline panel, as opposed to the enormous list that gets pasted around here.

Numbers rather than impressions, if you have them.

46 16GraceAZ_72, carl_compliance, DanielChem_CHI and 43 others
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COA_Karl
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Jan 2024
Pennsylvania
May 25, 2025 at 2:25 PM#2

This one has a reasonably settled answer, so here it is. Quarterly for the first year is convention rather than evidence, and it is defensible for a simple reason: it is roughly the interval over which HbA1c becomes informative again, since it reflects about three months of glycaemia. After the first year, and once doses are stable, annual is reasonable unless something specific is being followed.

I would rather be corrected than agreed with, if it comes to it.

45 15jim_asheville, matt_MKE, Dr.ReproEndo and 42 others
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MeganSA_TX
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San Antonio, TX
May 25, 2025 at 3:37 PM#3
COA_Karl said:
Quarterly for the first year is convention rather than evidence, and it is defensible for a simple reason: it is roughly the interval over which HbA1c…

Agreed, and reference ranges are laboratory-specific. Comparing your number to somebody else's range, or to a screenshot from another country, is how people convince themselves something is wrong.

Last edited: May 25, 2025 at 5:37 PM
44 14JessicaM_2024, TomFromTexas, mike.trainer_LA and 41 others
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mia_MS2
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Ann Arbor, MI
May 25, 2025 at 4:49 PM#4
tane_welly said:
I got a full panel before starting and a repeat at three months, and the second one is more useful than the first purely because I now have something…

Same position here, arrived at the long way round. A defensible baseline is short: HbA1c and fasting glucose, a lipid panel with ApoB if you can get it, ALT and AST, creatinine with eGFR, TSH, ferritin and B12, and a full blood count. That set catches the things that change, the things that explain symptoms, and the things that alter the prescribing decision. Almost everything else on the long circulating lists is either invariant, uninterpretable without a specific question, or an incidental finding waiting to cause an unnecessary workup.

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Dr.RenalNash
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Nashville, TN
May 25, 2025 at 11:47 PM#5

From the other side of the consultation, briefly.

Blood work came back perfect. baseline bloodwork + this community = winning. 🏆

42 12maria_elpaso, anders_CPH, Dr.NutriCornell and 39 others
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