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ForumsRetatrutide & Triple AgonistsGlucagon-mediated thermogenesis on retatrutide — looking for input Page 3

Glucagon-mediated thermogenesis on retatrutide — looking for input

SkepticalSean Sat, Jun 14, 2025 at 8:51 AM 17 replies 1,657 viewsPage 3 of 4
amsterdam_pete
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Jun 15, 2025 at 1:21 PM#11
Dr.NephBHM_UK said:
The honest answer is that the effect is real, the magnitude is contested, and the individual variation is larger than either.

Fair, and it stops being fair at the extremes. The middle of the range is well understood; the ends are where the honest answer is that nobody knows.

25 23JakeSmashed95, NauseaFreeNow, SteveThurs and 22 others
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mel_PDX
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Jun 16, 2025 at 2:05 AM#12
BrianDallas92 said:
The glucagon component looks paradoxical and is not.

Genuinely useful, thank you. I had the facts and not the framework.

Last edited: Jun 16, 2025 at 8:05 AM
26 24Dr.KarenChen, Dr.NateNeph, PharmD_Rodriguez and 23 others
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PharmD_Rodriguez
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Jun 16, 2025 at 2:49 PM#13
Dr.NephBHM_UK said:
The honest answer is that the effect is real, the magnitude is contested, and the individual variation is larger than either.

I do not accept the framing. The question has been narrowed to the version that has a tidy answer, and the part that was dropped is the part the OP actually asked about.

Last edited: Jun 16, 2025 at 7:49 PM
27 0robert_kc, dan_philly, MeganSA_TX and 24 others
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lisa_labSD
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Jun 17, 2025 at 3:32 AM#14

The figures, for anyone assembling their own picture. One habit that pays for itself: post the method alongside the number. A figure without its method cannot be checked, and an unchecked figure is how this community accumulates folklore.

28 1lori_vegas, Dr.PulmRoch, maya_sedona and 25 others
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Admin
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Jun 17, 2025 at 4:15 PM#15

Moderator note: reminder that nothing in this thread is medical advice, and that clinical claims need a source. Thread quality here is what the rules are for. Keep it up.

29 2PeptideSynthNJ, Dr.KarenChen, Dr.NateNeph and 26 others
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