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Evidence-based GLP-1 & peptide discussion since 2023
ForumsRetatrutide & Triple AgonistsRetatrutide cholesterol effects — need advice Page 6

Retatrutide cholesterol effects — need advice

labquiet_amy Sun, Mar 16, 2025 at 3:28 AM 56 replies 2,312 viewsPage 6 of 12
PedsEndoPhilly
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Apr 27, 2025 at 6:54 PM#26
Dr.ReproEndo said:
The mechanism and the magnitude are separate questions.

Adding the part of the answer the thread has not reached. It helps to say which part of this you are uncertain about. A precise question gets a precise answer; a general one gets everybody’s favourite anecdote.

22 20sarah_TO, wendy_avl, jason_paloalto and 19 others
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Dr.AddMedPHL
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May 3, 2025 at 6:13 AM#27

The figures, for anyone assembling their own picture. Worth stating the units and the reference range whenever you post a number here. A large fraction of the apparent disagreement in these threads is two people using different units and both being right.

23 21sarah_nash92, FitDadDave, RunnerRach and 20 others
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PharmacoVig_BOS
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May 8, 2025 at 5:29 PM#28

Following on from Dr.ReproEndo — and this may be the naive question:

What the phase 2 dropout pattern implies about how the phase 3 tolerability will read?

24 22DataDave, Dr.GutHealth, amsterdam_pete and 21 others
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DeniseRN_TPA
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May 14, 2025 at 4:42 AM#29
Dr.AddMedPHL said:
Worth stating the units and the reference range whenever you post a number here.

Careful with the causal language. Two things moving together in a period when five things changed is not a mechanism, and stating it as one makes the thread less useful to somebody reading it later.

Last edited: May 14, 2025 at 7:42 AM
25 23LindaRN_retired, tommy_boulder, hyun_seoul and 22 others
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labquiet_amy
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May 19, 2025 at 3:51 PM#30

Reporting back.

Resolved, and the thing that resolved it was the least interesting suggestion in the thread. Writing that down for the next person who wants the interesting answer.

Last edited: May 19, 2025 at 5:51 PM
47 20pete_manc_UK, anna.melb_AU, mark_tokyo and 44 others
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