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ForumsSemaglutide (Ozempic / Wegovy)Semaglutide and MASH — liver histology improvement data Page 5

Semaglutide and MASH — liver histology improvement data

MASHdoc_SA Wed, Jun 3, 2026 at 8:46 AM 22 replies 524 viewsPage 5 of 5
Dr.NateNeph
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Jun 5, 2026 at 12:23 PM#21

The figures, for anyone assembling their own picture. For anyone reading later: the numbers in this thread are worth checking against a primary source before you act on them, including mine. Half the figures circulating in this community trace back to a secondary summary that dropped a qualifier.

7 5JakeSmashed95, NauseaFreeNow, SteveThurs and 4 others
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GenomicsKate
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Jun 6, 2026 at 6:36 AM#22

One thing that is still open after Dr.NephBHM_UK’s answer:

Whether anyone has held at a sub-maximal dose long term and kept the result, or whether the maintenance data only exists at 2.4mg?

8 6KristenIndy, MarkLI_maint, Dr.PeteFamMed and 5 others
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Dr.LipidDallas
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Jun 7, 2026 at 12:48 AM#23
Dr.NateNeph said:
For anyone reading later: the numbers in this thread are worth checking against a primary source before you act on them, including mine.

Filing a mild objection. Mild because I might be wrong; an objection because nobody has addressed the case that does not fit. Filing an objection on the n=1 problem. Personal experience is genuine evidence about one person and very weak evidence about anybody else, and this thread keeps promoting the first into the second.

9 7cory_ATX, lori_vegas, Dr.PulmRoch and 6 others
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TirzTom
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Jun 7, 2026 at 7:00 PM#24
Dr.NateNeph said:
For anyone reading later: the numbers in this thread are worth checking against a primary source before you act on them, including mine.

Agreed on the substance. I would put less weight on the timescale, because two months of anything is not enough to distinguish a trend from a wobble.

Last edited: Jun 7, 2026 at 11:00 PM
10 8SandraNC_45, Dr.EndoIndy, tom_AK and 7 others
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emma_london
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Jun 8, 2026 at 1:11 PM#25
Dr.NateNeph said:
For anyone reading later: the numbers in this thread are worth checking against a primary source before you act on them, including mine.

Bookmarking. The distinction being drawn above is the one nobody else makes. Sending this to two other people who asked me the same thing last week.

Last edited: Jun 8, 2026 at 7:11 PM
11 9julia.endo, JessicaM_2024, TomFromTexas and 8 others
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