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ForumsMASH / Liver DiseaseALT normalization rates on GLP-1 — pooled trial data Page 4

ALT normalization rates on GLP-1 — pooled trial data

BethLabQueen Mon, Jun 8, 2026 at 2:45 AM 20 replies 530 viewsPage 4 of 4
Dr.RenalNash
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Jun 8, 2026 at 3:36 PM#16
rachel_ABQ said:
NASH/MAFLD therapeutic landscape and liver and MASH: GLP-1 agonists are emerging as potential first-line NASH therapy.

Mine went the same way, slower.

Last edited: Jun 8, 2026 at 8:36 PM
3 1wei_SG, cory_ATX, lori_vegas
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traveltech_sara
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Jun 8, 2026 at 5:16 PM#17
DoseLogDan said:
Liver imaging follow-up for liver and MASH: FibroScan at baseline showed CAP score 337 dB/m (moderate steatosis) and stiffness 9.8 kPa (possible…

That reframing is the part I needed.

4 2LarryQC_SD, wanda_boise, NurseAsh_DET and 1 other
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hyun_seoul
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Jun 8, 2026 at 6:57 PM#18

Adding the clinical framing, because it changes how the question reads.

Liver ultrasound comparison for liver and MASH: my hepatologist ordered serial ultrasounds to track NAFLD regression.

Baseline: "Moderate hepatic steatosis, liver span 17.2cm, echogenic texture consistent with fat infiltration"
Month 8: "Mild steatosis, liver span 15.8cm, improved echogenicity"
Month 14: "Minimal to no steatosis, normal liver span 14.5cm, normal echotexture"

My liver literally shrank and de-fattened. The ultrasound tech said she's seen this pattern increasingly in GLP-1 patients and it's remarkable how consistently the fatty liver resolves.

5 3MASHdoc_SA, GenomicsKate, Dr.ObesityMed and 2 others
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bri_stats
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Jun 8, 2026 at 8:37 PM#19
hyun_seoul said:
Liver ultrasound comparison for liver and MASH: my hepatologist ordered serial ultrasounds to track NAFLD regression.

Same pattern here, and in the same order.

Last edited: Jun 9, 2026 at 12:37 AM
6 4JessicaM_2024, TomFromTexas, mike.trainer_LA and 3 others
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Admin
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Jun 8, 2026 at 10:18 PM#20

Moderator note: a post naming a supplier has been edited. Discuss suppliers in the review sections, not here. Thread quality here is what the rules are for. Keep it up.

28 1PeptideSynthNJ, Dr.KarenChen, Dr.NateNeph and 25 others
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