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Evidence-based GLP-1 & peptide discussion since 2023
ForumsMASH / Liver DiseaseDe novo lipogenesis reduction on GLP-1 — looking for input Page 4

De novo lipogenesis reduction on GLP-1 — looking for input

kate.chem Sat, Mar 28, 2026 at 11:30 AM 30 replies 896 viewsPage 4 of 6
Dr.SurgeonPGH
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Mar 29, 2026 at 11:56 AM#16
Dr.LipidDallas said:
It helps to say which part of this you are uncertain about.

Same experience, arrived at from the opposite direction.

20 18DoseLogDan, SleepFixSam, PurityPaulOR and 17 others
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mike_nyc
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Mar 29, 2026 at 2:43 PM#17

Following on from LabKate — and this may be the naive question:

How long did you give it before you decided it was working?

Last edited: Mar 29, 2026 at 6:43 PM
21 19stefan_berlin, Dr.EM_Chicago, pete_RVA and 18 others
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andrew_nyc
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Mar 29, 2026 at 5:30 PM#18
Dr.PathRoch said:
Say what you would expect to see if you were wrong, before you look.

Filing a mild objection. Mild because I might be wrong; an objection because nobody has addressed the case that does not fit. The objection nobody has made: this only works if the measurement is doing what we assume it is doing, and that assumption has not been tested here.

Last edited: Mar 29, 2026 at 10:30 PM
22 20PharmD_Rodriguez, julia.endo, JessicaM_2024 and 19 others
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JakeSmashed95
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Mar 29, 2026 at 8:17 PM#19
Dr.PathRoch said:
Say what you would expect to see if you were wrong, before you look.

That is right for the common case. Whether it is right for the case being asked about depends on a detail that has not been given.

23 21Dr.LipidDallas, alex_tucson, kevin_tulsa and 20 others
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mike_mod
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Mar 29, 2026 at 11:04 PM#20

Moderator note: reminder that nothing in this thread is medical advice, and that clinical claims need a source.

45 18PurityPaulOR, MaxMetOK, MounjBrad and 42 others
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