Dr.EndoIndy said:The mechanism and the magnitude are separate questions.
This is my experience too, for whatever a second data point is worth.
Dr.EndoIndy said:The mechanism and the magnitude are separate questions.
Coming at Dr.EndoIndy’s question from a different direction. Most of what circulates confidently in this community traces back to one summary of one study, and the qualifier was dropped somewhere in the third retelling.
Adding the numbers, since they settle part of this. If you are going to change something, change one thing and give it long enough to express itself. Four weeks is the usual minimum for anything pharmacological on this board, and two weeks of data has told you almost nothing.
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Browse GL BiochemOne thing that is still open after Dr.EndoIndy’s answer:
What did you change at the same time, and can you separate the two now?
stefan_berlin said:If you are going to change something, change one thing and give it long enough to express itself.
Pushing back on stefan_berlin here. I think the framing smuggles in the conclusion. Ask it the other way round and the obvious answer reverses, which usually means the question is doing the work.
Ask again with the specifics and you will get a better answer than this one.