🍪 CompoundTalk uses cookies to improve your experience, analyze traffic, and personalize content. By continuing to use this site, you agree to our Cookie Policy.
Evidence-based GLP-1 & peptide discussion since 2023
ForumsSide Effects & ManagementInsomnia on semaglutide — circadian rhythm disruption or weight loss related? Page 4

Insomnia on semaglutide — circadian rhythm disruption or weight loss related?

Dr.SleepRoch Thu, May 7, 2026 at 12:08 AM 21 replies 761 viewsPage 4 of 5
josh_phd_bmore
Member
389
1,678
Jul 2024
Baltimore, MD
May 14, 2026 at 8:51 AM#16
Dr.SurgeonPGH said:
Dr.SleepRoch said: ...but the FDA says semaglutide...

Mine went the same way, slower.

26 24NurseKim_ATL, paul_denver, TinaHashiRN and 23 others
Reply Quote Save Share Report
fiona_VT
Member
178
890
Dec 2024
Vermont
May 15, 2026 at 10:22 AM#17
LabKate said:
Say what you would expect to see if you were wrong, before you look.

There is a second half to this that has not been said yet. Order of operations matters more than any single choice here: establish a baseline, change one thing, wait long enough for it to express itself, then measure again under the same conditions.

27 0hans_munich, jason_sac26, chris_chi24 and 24 others
Reply Quote Save Share Report
stefan_berlin
Member
234
1,123
Oct 2024
Berlin, DE
May 16, 2026 at 11:53 AM#18

Adding the numbers, since they settle part of this. Worth stating the units and the reference range whenever you post a number here. A large fraction of the apparent disagreement in these threads is two people using different units and both being right.

28 1KevinCompounds, TirzTom, TrialTracker_MD and 25 others
Reply Quote Save Share Report

PeptideMeter — Independent Peptide Analytics

Community-driven peptide testing and vendor rating platform. Transparent results. Unbiased analysis. Trusted by thousands.

View Results
FDA_TrackerJim
Senior Member
1,567
7,890
Feb 2024
Rockville, MD
May 17, 2026 at 1:23 PM#19

Following on from LabKate — and this may be the naive question:

What the dose-response curve actually looks like above 1.7mg, because the trial means hide how few people account for the extra loss?

29 2Dr.LeslieOBGYN, MikeNYC_runner and 26 others
Reply Quote Save Share Report
mike_mod
Moderator
7,234
19,823
Nov 2023
New York
Online
May 18, 2026 at 2:53 PM#20

Moderator note: two posts asking for a source have been merged into one. Please search the thread before asking again. No action needed from anybody.

1 24PurityPaulOR
Reply Quote Save Share Report

Similar Threads

Nausea incidence by dose tier — STEP and SURMOUNT meta-analysis16 replies
Constipation on GLP-1: pathophysiology and fiber protocol5 replies
Alopecia on GLP-1 — telogen effluvium differential diagnosis3 replies
Gallbladder disease risk — cholelithiasis data from clinical trials12 replies
Pancreatitis risk assessment — pooled safety analysis15 replies
ForumsNewTrendingMembersAccount

Log In

Forgot password?
No account? Register