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Evidence-based GLP-1 & peptide discussion since 2023
ForumsProgress & Lab Results[PREMIUM] From wheelchair-bound to hiking again — 89 lbs lost photo documentation

[PREMIUM] From wheelchair-bound to hiking again — 89 lbs lost photo documentation

rachel_ABQ Mon, Apr 27, 2026 at 11:17 AM 26 replies 745 viewsPage 1 of 6
rachel_ABQ
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Albuquerque, NM
Apr 27, 2026 at 11:17 AM#1

Thirteen weeks at the same dose with no change on the scale, and I have gone from assuming it was the drug to assuming it was me and back several times.

The question I want answered is how to distinguish a genuine plateau from measurement noise and creeping intake, before changing anything.

Numbers rather than impressions, if you have them.

7 2nick_newbie, DadBodDave, AmyNC_wife and 4 others
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Dr.ObesityLA
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Dec 2023
Los Angeles, CA
Apr 27, 2026 at 11:29 AM#2
rachel_ABQ said:
Thirteen weeks at the same dose with no change on the scale, and I have gone from assuming it was the drug to assuming it was me and back several…

Plateau breaking story with a stall: I stalled at 196 lbs for 5 weeks. Tried everything — calorie cycling, increased exercise, more water. Nothing worked.

What finally broke the plateau: switching from evening to morning injection. Lost 11 lbs in the next 2 weeks. Plateaus are temporary — they always break if you stay consistent.

6 1KarenAZ_mom, zoe_NC, Dr.ObesityLA and 3 others
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Dr.MetabolicMD
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Apr 27, 2026 at 11:41 AM#3
Dr.ObesityLA said:
Plateau breaking story with a stall: I stalled at 196 lbs for 5 weeks.

Agreeing with Dr.ObesityLA, and the qualification matters more than the agreement. Genuine plateaus happen too, and the mechanism is metabolic adaptation plus a smaller body. A body 20kg lighter needs meaningfully fewer calories at rest and less to move, so the deficit that produced the first phase is arithmetically smaller now. The options are the honest ones — increase the deficit slightly, increase activity, or accept the new plateau — and escalating the dose is only one of them.

5 0HealthEcon_DC, PedsEndoPhilly, SleepDoc_PDX and 2 others
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emily_PDX
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Nov 2024
Portland, OR
Apr 27, 2026 at 11:54 AM#4
rachel_ABQ said:
Thirteen weeks at the same dose with no change on the scale, and I have gone from assuming it was the drug to assuming it was me and back several…

Mine went the same way, slower.

Last edited: Apr 27, 2026 at 1:54 PM
4 24Dr.KarenChen, Dr.NateNeph, PharmD_Rodriguez and 1 other
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Dr.EndoIndy
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Oct 2024
Indianapolis, IN
Apr 27, 2026 at 1:00 PM#5

Clinical perspective, offered as context rather than as advice. Start from the measurement rather than the conclusion. Almost every disagreement here turns out to be two people measuring different things and comparing the numbers anyway.

3 23SandraNC_45, Dr.EndoIndy, tom_AK
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Amazing transformation! Starting at 287 lbs, I'm now at 162 lbs after 18 months on semaglutide 2.4mg/wk. These photos show my progress at months 3, 6, 9, 12, 15, and 18. The body recomposition has been incredible — DEXA shows 23% body fat, down from 42%...

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